Orcutt Sonia T, O'Donoghue Cristina, Smith Paul, Laronga Christine
From the Department of Breast Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, and the Department of Plastic Surgery, University of South Florida, Tampa.
South Med J. 2017 Oct;110(10):654-659. doi: 10.14423/SMJ.0000000000000707.
The use of mastectomy has increased in patients who are high-risk genetic carriers who need or desire mastectomy for prophylactic reasons, as well as for patients who have breast cancer and need or desire mastectomy for treatment of their cancer. Retaining the nipple and skin with a nipple-sparing mastectomy results in improved patient satisfaction as compared with traditional mastectomy, without compromise of oncologic principles. This technique has been performed in patients with small, peripherally located tumors and nonptotic breasts; in recent years, however, consideration has been given to patients with more centrally located, larger tumors, and patients undergoing radiation or with ptotic breasts with the potential for poor cosmetic outcome. As the use of nipple-sparing mastectomy increases, it is important to continually assess the eligibility of patients for this technique.
对于因预防性原因需要或希望进行乳房切除术的高危基因携带者患者,以及患有乳腺癌且因癌症治疗需要或希望进行乳房切除术的患者,乳房切除术的使用有所增加。与传统乳房切除术相比,保留乳头和皮肤的保乳手术能提高患者满意度,同时不影响肿瘤学原则。该技术已应用于肿瘤较小、位于周边且乳房不下垂的患者;然而近年来,对于肿瘤位置更靠近中央、体积更大的患者,以及接受放疗的患者或乳房下垂可能导致美容效果不佳的患者,也开始考虑采用该技术。随着保乳手术的应用增加,持续评估患者是否适合该技术非常重要。