Gustafson Y, Berggren D, Brännström B, Bucht G, Norberg A, Hansson L I, Winblad B
Department of Geriatric Medicine, University of Umeå, Sweden.
J Am Geriatr Soc. 1988 Jun;36(6):525-30. doi: 10.1111/j.1532-5415.1988.tb04023.x.
The aims of this study were to estimate the incidence of acute confusional state (ACS), its predisposing factors and consequences in 111 consecutive patients operated for fractured neck of the femur. The incidence of ACS was 61 percent and the predicting factors were old age and dementia. Drugs with anticholinergic effect, depression, and previous stroke were factors that seemed to be associated with the development of ACS. Ninety-two percent of the patients who had severe perioperative blood pressure drops developed ACS. The consequences of ACS were prolonged ward-stay at the orthopedic department, a greater need for long-term care after discharge, and poor walking ability at discharge and six months after surgery. The confused patients also had more complications, such as urinary problems, feeding problems and decubital ulcers, as compared with the nonconfused patients.
本研究的目的是评估111例连续接受股骨颈骨折手术患者的急性意识模糊状态（ACS）发生率、其诱发因素及后果。ACS的发生率为61%，预测因素为高龄和痴呆。具有抗胆碱能作用的药物、抑郁和既往中风似乎是与ACS发生相关的因素。92%围手术期血压严重下降的患者发生了ACS。ACS的后果包括在骨科病房住院时间延长、出院后对长期护理的需求增加，以及出院时和术后6个月行走能力较差。与意识未模糊的患者相比，意识模糊的患者还出现更多并发症，如泌尿系统问题、喂养问题和压疮。
