Cohen A H
Section of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853.
J Neurobiol. 1988 Apr;19(3):193-8. doi: 10.1002/neu.480190302.
Recently evidence was presented that, following transection, spinal cords of larval lampreys could regenerate functional connections. The demonstration in isolated spinal cord-notochord preparations consisted of fictive swimming coordinated across the lesion site. In the study reported here curare was added to the bath to eliminate the possible contribution from reflexes mediated by contractions from any remaining muscle fibers attached to the notochord. Coordination remained in the presence of curare, adding further evidence that indeed the regenerated fibers formed functionally appropriate connections.
最近有证据表明，幼体七鳃鳗的脊髓在横切后能够再生功能连接。在分离的脊髓-脊索标本中的演示包括在损伤部位协调的虚构游泳。在本文报道的研究中，将箭毒添加到浴液中，以消除附着在脊索上的任何剩余肌肉纤维收缩介导的反射可能产生的影响。在箭毒存在的情况下仍保持协调，这进一步证明再生纤维确实形成了功能上合适的连接。
