Kheir Abdelmoneim E M, Ibrahim Salah A, Abdelsatir Azza, Bahar Mustafa E
Department of Paediatrics and Child Health, Faculty of Medicine, University of Khartoum, Khartoum, Sudan.
Department of Paediatrics and Child Health, Faculty of Medicine, University of Khartoum and Soba University Hospital, P.O. Box 102, Khartoum, Sudan.
J Med Case Rep. 2017 Oct 4;11(1):283. doi: 10.1186/s13256-017-1446-5.
The Bacillus Calmette-Guérin vaccine, which is used for the prevention of tuberculosis, is considered protective against the severe forms of childhood tuberculosis. However, some serious adverse reactions including osteitis of the long bones can occur.
We report a case of an 18-month-old Sudanese girl who presented at the age of 3 months with swelling of her left forearm following Bacillus Calmette-Guérin vaccination administered at birth. Radiological and histological investigations confirmed tuberculous osteitis of the distal radius. She responded very well to antituberculous treatment with complete healing at follow-up visits. To the best of our knowledge this is the first case report of osteitis of the radius following Bacillus Calmette-Guérin vaccination described from Sudan.
Bacillus Calmette-Guérin osteitis, although rare, should be considered a possible complication of the Bacillus Calmette-Guérin vaccination, and early diagnosis and treatment are essential.
用于预防结核病的卡介苗被认为可预防儿童严重形式的结核病。然而,可能会出现一些严重不良反应,包括长骨骨炎。
我们报告一例18个月大的苏丹女孩,她在3个月大时因出生时接种卡介苗后出现左前臂肿胀。放射学和组织学检查证实为桡骨远端结核性骨炎。她对抗结核治疗反应良好,随访时完全愈合。据我们所知,这是苏丹首例关于卡介苗接种后桡骨骨炎的病例报告。
卡介苗性骨炎虽然罕见,但应被视为卡介苗接种可能的并发症,早期诊断和治疗至关重要。