Department of Oncology and Ludwig Cancer Research, University of Lausanne, Switzerland.
Cancer Discov. 2017 Oct;7(10):1062-1064. doi: 10.1158/2159-8290.CD-17-0858.
Characterization of intratumoral leukocyte populations may help in estimating patients' prognosis and predictions. A new study shows remarkable differences between the and invasive breast cancer stages and highlights that cell number analyses should be complemented with characterization of T-cell functions, increasing the likelihood that immune competent antitumor T cells and further biomarkers are identified for guiding therapy choices. .
肿瘤内白细胞群体的特征分析有助于评估患者的预后和预测。一项新的研究表明,在 和浸润性乳腺癌阶段之间存在显著差异,并强调细胞数量分析应该辅以 T 细胞功能的特征分析,从而增加识别具有免疫功能的抗肿瘤 T 细胞和其他生物标志物的可能性,以指导治疗选择。