Department of Neurology, Chinese PLA General Hospital, Beijing, 100853, PR China.
School of Medicine, Nankai University, Tianjin, 300071, PR China.
Sci Rep. 2017 Oct 3;7(1):12595. doi: 10.1038/s41598-017-12802-9.
Headache is increasingly being reported as a detrimental effect of mobile phone (MP) use. However, studies aimed to investigate the association between MP use and headache yielded conflicting results. To assess the consistency of the data on the topic, we performed a systematic review and meta-analysis of the available cross-sectional studies. Published literature from PubMed and other databases were retrieved and screened, and 7 cross-sectional studies were finally included in this meta-analysis. The pooled odds ratio (OR) and 95% confidence interval (CI) were calculated. We found that the risk of headache was increased by 38% in MP user compared with non-MP user (OR, 1.38; 95% CI, 1.18-1.61, p < 0.001). Among MP users, the risk of headache was also increased in those who had longer daily call duration (2-15 min vs. <2 min: OR, 1.62; 95% CI, 1.34-1.98, p < 0.001; >15 min vs. <2 min: OR, 2.50; 95% CI, 1.76-3.54, p < 0.001) and higher daily call frequency (2-4 calls vs. <2 calls: OR, 1.37; 95% CI, 1.07-1.76, p < 0.001; >4 calls vs. <2 calls: OR, 2.52; 95% CI, 1.78-3.58, p < 0.001). Our data indicate that MP use is significantly associated with headache, further epidemiologic and experimental studies are required to affirm and understand this association.
头痛越来越多地被报道为手机（MP）使用的有害影响。然而，旨在调查 MP 使用与头痛之间关联的研究得出了相互矛盾的结果。为了评估该主题数据的一致性，我们对现有的横断面研究进行了系统回顾和荟萃分析。从 PubMed 和其他数据库中检索和筛选已发表的文献，最终有 7 项横断面研究纳入本荟萃分析。计算合并的比值比（OR）和 95%置信区间（CI）。我们发现，与非 MP 用户相比，MP 用户头痛的风险增加了 38%（OR，1.38；95%CI，1.18-1.61，p<0.001）。在 MP 用户中，每日通话时间较长（2-15 分钟与<2 分钟：OR，1.62；95%CI，1.34-1.98，p<0.001；>15 分钟与<2 分钟：OR，2.50；95%CI，1.76-3.54，p<0.001）和每日通话频率较高（2-4 次通话与<2 次通话：OR，1.37；95%CI，1.07-1.76，p<0.001；>4 次通话与<2 次通话：OR，2.52；95%CI，1.78-3.58，p<0.001）的患者头痛风险也增加。我们的数据表明，MP 使用与头痛显著相关，需要进一步的流行病学和实验研究来证实和理解这种关联。
