Cies Jeffrey J, Moront Matthew L, Moore Ii Wayne S, Ostrowicki Renata, Gannon Kelsey B, Da-Silva Shonola S, Chopra Arun, Parker Jason
St. Christopher's Hospital for Children, Philadelphia, PA, 19134, USA.
Drexel University College of Medicine, Philadelphia, PA, 19129, USA.
Pharmacy (Basel). 2015 Oct 19;3(4):197-209. doi: 10.3390/pharmacy3040197.
, To survey the pediatric trauma programs to ascertain if and how etomidate is being used for rapid sequence intubation (RSI) in pediatric trauma patients. , A 25 question survey was created using REDCaps. A link to the survey was emailed to each of the pediatric and adult trauma programs that care for pediatric patients. , Pediatric trauma programs and adult trauma programs caring for pediatric patients. , None. , A total of 16% of programs responded (40/247). The majority of the centers that responded are urban, academic, teaching Level 1 pediatric trauma centers that provide care for > 200 pediatric trauma patients annually. The trauma program directors were the most likely to respond to the survey (18/40). 33/38 respondents state they use etomidate in their RSI protocol but it is not used in all pediatric trauma patients. 26/38 respondents believe that etomidate is associated with adrenal suppression and 24/37 believe it exacerbates adrenal suppression in pediatric trauma patients yet 28 of 37 respondents do not believe it is clinically relevant. , Based on the results of the survey, the use of etomidate in pediatric trauma patients is common among urban, academic, teaching, level 1 pediatric trauma centers. A prospective evaluation of etomidate use for RSI in pediatric trauma patients to evaluate is potential effects on adrenal suppression and hemodynamics is warranted.
调查儿科创伤项目,以确定依托咪酯是否以及如何用于儿科创伤患者的快速顺序诱导插管(RSI)。使用REDCaps创建了一份包含25个问题的调查问卷。调查问卷的链接通过电子邮件发送给了每一个照顾儿科患者的儿科和成人创伤项目。儿科创伤项目以及照顾儿科患者的成人创伤项目。无。共有16%的项目回复(40/247)。回复的大多数中心是城市、学术性的一级儿科创伤教学中心,每年为超过200名儿科创伤患者提供护理。创伤项目主任最有可能回复调查问卷(18/40)。33/38的受访者表示他们在RSI方案中使用依托咪酯,但并非所有儿科创伤患者都使用。26/38的受访者认为依托咪酯与肾上腺抑制有关,24/37的受访者认为它会加重儿科创伤患者的肾上腺抑制,但37名受访者中有28人认为这在临床上并不相关。基于调查结果,依托咪酯在儿科创伤患者中的使用在城市、学术性的一级儿科创伤中心很常见。有必要对依托咪酯在儿科创伤患者RSI中的使用进行前瞻性评估,以评估其对肾上腺抑制和血流动力学的潜在影响。