Park C B
University of Hawaii School of Public Health, Honolulu 96822.
Parasitology. 1988 Apr;96 ( Pt 2):265-71. doi: 10.1017/s0031182000058261.
A new method of computing the infectivity index of microfilariae (mf) for the mosquito population is proposed using the estimated mf density distribution in the human population. the observed density distribution is considered a compound of the Poisson and the gamma distributions. The former distribution describes the probability of a specimen containing a specified number of mf and the latter describes the density distribution of mf in the host population. The mf infectivity index is the probability that a blood meal will include at least 1 mf, conditional on the population-density distribution of mf as specified by the gamma distribution. Actual data indicate that this population-density-based infectivity index can be considerably different from the conventional index based on the survey-density distribution. The level of the carrier rate of mf in a survey is greatly influenced, apart from the sample variation, by the average volume of blood taken from each person. The rate computed on the estimated population-density distribution of mf is convertible to any base amount of blood.
提出了一种利用人群中估计的微丝蚴（mf）密度分布来计算蚊虫群体微丝蚴感染性指数的新方法。观察到的密度分布被认为是泊松分布和伽马分布的复合分布。前一种分布描述了一个标本含有特定数量微丝蚴的概率，后一种分布描述了宿主群体中微丝蚴的密度分布。微丝蚴感染性指数是指在伽马分布规定的微丝蚴群体密度分布条件下，一次吸血至少包含1条微丝蚴的概率。实际数据表明，这种基于群体密度的感染性指数可能与基于调查密度分布的传统指数有很大差异。除样本变异外，调查中微丝蚴携带者率的水平还受到从每个人采集的平均血量的极大影响。根据微丝蚴估计群体密度分布计算出的率可转换为任何基准血量。
