孕妇中的登革热：2007 - 2015年巴西病例特征

Dengue in pregnant women: characterization of cases in Brazil, 2007-2015.

作者信息

Nascimento Laura Branquinho do, Siqueira Cláudio Morais, Coelho Giovanini Evelim, Siqueira João Bosco

机构信息

Universidade Federal de Goiás, Instituto de Patologia Tropical e Saúde Pública, Goiânia-GO, Brasil.

Ministério da Saúde, Secretaria de Vigilância em Saúde, Brasília-DF, Brasil.

出版信息

Epidemiol Serv Saude. 2017 Jul-Sep;26(3):433-442. doi: 10.5123/S1679-49742017000300002.

DOI:10.5123/S1679-49742017000300002

PMID:28977169

Abstract

OBJECTIVE

to characterize the probable cases of dengue in pregnant women reported in Brazil, from 2007 to 2015.

METHODS

descriptive study of sociodemographic, epidemiological, clinical and laboratory characteristics, with data from the Information System for Notifiable Diseases (Sinan).

RESULTS

the annual incidence of dengue in pregnant women ranged from 3.3 (2009) to 816.6 (2010) cases per 100 thousand live births; of the 43,772 probable cases of dengue in pregnant women, 81.6% were investigated, 34.1% were confirmed by laboratory tests, and 1.7% were severe cases; hospitalization and fatality rates were of 5.4% and 1.6‰, respectively; the risk of death due to dengue was higher in pregnant women than in the population of non-pregnant women at reproductive age (ratio=3.95; 95%CI=3.07;5.08), and higher in the third trimester of pregnancy (ratio=8.55; 95%CI=6.08;12.02).

CONCLUSION

the results show the burden of dengue in pregnant women and their vulnerability to worsening of the disease and death.

摘要

目的

描述2007年至2015年巴西报告的孕妇登革热疑似病例情况。

方法

利用法定传染病信息系统（Sinan）的数据，对社会人口学、流行病学、临床和实验室特征进行描述性研究。

结果

孕妇登革热的年发病率为每10万活产儿3.3例（2009年）至816.6例（2010年）；在43772例孕妇登革热疑似病例中，81.6%接受了调查，34.1%经实验室检测确诊，1.7%为重症病例；住院率和死亡率分别为5.4%和1.6‰；孕妇因登革热死亡的风险高于育龄非孕妇人群（比值=3.95；95%置信区间=3.07；5.08），且在妊娠晚期更高（比值=8.55；95%置信区间=6.08；12.02）。