Sinha Ruchita, Datta Mamta Rath, Singh Vinita
Manipal Tata Medical College, Jamshedpur, Jharkhand, India.
Department of Obg., Tata Main Hospital, Jamshedpur, Jharkhand, India.
J Family Med Prim Care. 2022 Mar;11(3):912-917. doi: 10.4103/jfmpc.jfmpc_633_21. Epub 2022 Mar 10.
Dengue fever is a major health problem with high morbidity and mortality especially during epidemic season; pregnant females being no exception. But, there is paucity of published data on dengue fever during pregnancy. Hence, this study was planned to study the clinical profile, maternal outcome and predictors of poor outcome in pregnant dengue patients.
All pregnant females attending labour room of Tata Main Hospital, Jamshedpur from April 2016 to October2020 with acute febrile illness caused by dengue virus at any gestational age were included in the study. Diagnosis of dengue was made by detection of NS1 antigen or dengue serology. A predesigned proforma was used to record materno-foetal outcomes and were analysed.
Dengue was the cause of fever in 7.1% febrile patients. Maternal complications included abortions (26%), abruptio (1.9%), postpartum haemorrhage (11.9%) . Of all the pregnant dengue patients, five had severe dengue(SD) with high mortality (3/5; 60%). Fetal complications were intrauterine death(7.7%),preterm(42.3%). Thrombocytopenia and elevated transaminases were associated with adverse outcome.
Dengue fever in pregnancy is associated with poor outcomes more in cases of SD rather than dengue fever . Pregnant females with high risk predictors should be identified and managed aggressively in intensive care units to improve outcomes.
登革热是一个主要的健康问题,发病率和死亡率都很高,尤其是在流行季节;孕妇也不例外。但是,关于孕期登革热的已发表数据很少。因此,本研究旨在探讨妊娠登革热患者的临床特征、孕产妇结局及不良结局的预测因素。
纳入2016年4月至2020年10月在贾姆谢德布尔塔塔主医院产房就诊的所有孕妇,她们在任何孕周因登革热病毒引起急性发热性疾病。通过检测NS1抗原或登革热血清学进行登革热诊断。使用预先设计的表格记录母婴结局并进行分析。
登革热是7.1%发热患者发热的原因。孕产妇并发症包括流产(26%)、胎盘早剥(1.9%)、产后出血(11.9%)。在所有妊娠登革热患者中,5例患有严重登革热(SD),死亡率高(3/5;60%)。胎儿并发症为宫内死亡(7.7%)、早产(42.3%)。血小板减少和转氨酶升高与不良结局相关。
孕期登革热与严重登革热病例的不良结局关联更大,而非普通登革热。应识别具有高风险预测因素的孕妇,并在重症监护病房积极进行管理,以改善结局。