比较加热湿化高流量鼻导管与持续气道正压通气在极低出生体重儿拔管后时期的疗效。
To Compare the Efficacy of Heated Humidified High-Flow Nasal Cannula and Continuous Positive Airway Pressure in Post-Extubation Period in VLBW Infants.
作者信息
Garg Bhawan Deep, Bajaj Naveen, Sharma Deepak
机构信息
Deep hospital, Ludhiana, Punjab, India.
Department of Neonatology, National Institute of Medical Sciences, Jaipur, Rajasthan, India.
出版信息
J Trop Pediatr. 2018 Aug 1;64(4):262-266. doi: 10.1093/tropej/fmx057.
OBJECTIVE
The objective of this study was to compare efficacy of continuous positive airway pressure (CPAP) and heated humidified high-flow nasal cannula (HHHFNC) as noninvasive respiratory support in post-extubation period in very low birth weight (VLBW) infants.
METHOD
This retrospective study enrolled 136 neonates, ≤32 weeks gestation and ≤1500 grams birth weight, requiring noninvasive respiratory support during post-extubation period.
RESULTS
There was no significant difference in post-extubation failure in HHHFNC group when compared with CPAP group (p > 0.05) but post-extubation complication was significantly higher in CPAP group (p < 0.05) including nasal septal trauma and pneumothorax.
CONCLUSIONS
In neonates ≤32 weeks of gestational age, HHHFNC showed similar efficacy, and better safety profile than nasal-CPAP when used during post-extubation period for respiratory support.
目的
本研究的目的是比较持续气道正压通气（CPAP）和温热湿化高流量鼻导管（HHHFNC）作为极低出生体重（VLBW）婴儿拔管后无创呼吸支持的疗效。
方法
这项回顾性研究纳入了136例孕周≤32周、出生体重≤1500克且在拔管后需要无创呼吸支持的新生儿。
结果
与CPAP组相比，HHHFNC组拔管失败无显著差异（p>0.05），但CPAP组拔管后并发症显著更高（p<0.05），包括鼻中隔创伤和气胸。
结论
在孕周≤32周的新生儿中，HHHFNC在拔管后用于呼吸支持时显示出相似的疗效，且安全性优于鼻CPAP。
Zotero 插件