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通过X染色体短臂探针L1.28(DXS7)鉴定出的不同种族群体中的DNA多态性。

DNA polymorphisms, identified by an X-chromosome short-arm probe L 1.28 (DXS7), in different racial groups.

作者信息

Papiha S S, Bhattacharya S S, Roberts D F

机构信息

Department of Human Genetics, University of Newcastle upon Tyne, UK.

出版信息

Hum Hered. 1988;38(2):72-5. doi: 10.1159/000153761.

Abstract

Restriction fragment length polymorphisms of the L1.28 probe which is closely linked to X-linked disorders, retinitis pigmentosa and Norrie disease, were studied in samples from England, India and Nigeria. The frequency of the A2 allele (9-kb fragment) was 0.23, 0.55 and 0.46 in England, India and Nigeria, respectively. The differences between the English and Indian populations were highly significant.

摘要

对与X连锁疾病、色素性视网膜炎和诺里病紧密连锁的L1.28探针的限制性片段长度多态性进行了研究,研究样本来自英格兰、印度和尼日利亚。在英格兰、印度和尼日利亚,A2等位基因(9千碱基片段)的频率分别为0.23、0.55和0.46。英格兰和印度人群之间的差异非常显著。

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