Nagayama Masao, Yang Sunghoon, Geocadin Romergryko G, Kaplan Peter W, Hoshiyama Eisei, Shiromaru-Sugimoto Azusa, Kawamura Mitsuru
Department of Neurology, International University of Health and Welfare School of Medicine, Narita, Chiba, Japan.
Department of Neurology and the Center for Stroke and Neurocritical Care, International University of Health and Welfare Atami Hospital, Atami, Shizuoka, Japan.
F1000Res. 2017 Sep 15;6:1690. doi: 10.12688/f1000research.10939.1. eCollection 2017.
Nonconvulsive status epilepticus (NCSE) has rapidly expanded from classical features such as staring, repetitive blinking, chewing, swallowing, and automatism to include coma, prolonged apnea, cardiac arrest, dementia, and higher brain dysfunction, which were demonstrated mainly after the 2000s by us and other groups. This review details novel clinical features of NCSE as a manifestation of epilepsy, but one that is underdiagnosed, with the best available evidence. Also, we describe the new concept of epilepsy-related organ dysfunction (Epi-ROD) and a novel electrode and headset which enables prompt electroencephalography.
非惊厥性癫痫持续状态（NCSE）已从诸如凝视、反复眨眼、咀嚼、吞咽和自动症等经典特征迅速扩展，涵盖昏迷、长时间呼吸暂停、心脏骤停、痴呆和高级脑功能障碍等情况，这些主要是我们和其他研究团队在21世纪初之后证实的。本综述依据现有最佳证据，详细阐述了NCSE作为癫痫一种表现形式的新临床特征，但其常被漏诊。此外，我们还介绍了癫痫相关器官功能障碍（Epi-ROD）的新概念以及一种能够实现快速脑电图检查的新型电极和头戴设备。
