Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia; Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Department of Dialysis, University Medical Centre Maribor, Maribor, Slovenia; Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Eur J Intern Med. 2017 Nov;45:54-58. doi: 10.1016/j.ejim.2017.09.041. Epub 2017 Oct 2.
Acute kidney injury (AKI) is common in critically ill patients and is associated with high morbidity and mortality. The availability of several biomarkers of kidney injury offers new tools for its early recognition and management. The early identification of high-risk patients provides an opportunity to develop strategies for the prevention, early diagnosis and treatment of AKI. Despite progress in critical care medicine over the past decade, the treatment strategies for AKI in critically ill patients, such as when to start renal replacement therapy, remain controversial. A recently proposed risk prediction score for AKI, based on routinely available clinical variables, presents a new means of identifying patients at high risk of AKI.
急性肾损伤（AKI）在危重症患者中很常见，与高发病率和死亡率相关。多种肾损伤生物标志物的出现为其早期识别和管理提供了新的工具。高危患者的早期识别为 AKI 的预防、早期诊断和治疗提供了机会。尽管过去十年重症监护医学取得了进展，但危重症患者 AKI 的治疗策略，例如何时开始肾脏替代治疗，仍然存在争议。最近提出的基于常规临床变量的 AKI 风险预测评分提供了一种新的方法，可以识别出高危 AKI 患者。
