Mozafarpour Sarah, Kajbafzadeh Abdol-Mohammad, Abbasioun Reza, Habibi Ali Akbar, Nabavizadeh Behnam
Department of Urology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Pediatric Urology and Regenerative Medicine Research Center, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
Urology. 2017 Aug;106:231-232. doi: 10.1016/j.urology.2017.03.037. Epub 2017 Apr 25.
Hypospadias is a common congenital malformation of the male genital tract. The most frequent complication after hypospadias repair is urethrocutaneous fistula. Its incidence has been reported up to 35% worldwide. The diagnosis of these fistulas is sometimes challenging particularly with tiny and multiple fistulas. Usually, parents complain of urinary spraying, sprinkling, or passing a single stream of urine from the undersurface of the penis after the surgery. Urethrocutaneous fistulas are not always visible on physical examination. Locating the fistula and status of the surrounding skin is very important in order to choose the surgical repair technique. The patency and anatomy of the distal urethra should also be determined before the repair surgery. That is why urologists usually use retrograde urethrography or cystoscopy to find the location of fistula. However, these modalities have their own risk for children and are not always helpful. Sometimes the contrast media inserted can clog some fistulas especially near the glans and preclude the diagnosis. We present an easy technique to screen for urethrocutaneous fistulas after hypospadias surgery.
In this technique (Video 1), an antibiotic ointment is inserted through the meatus while the base of the penis is held; the ointment is then gently pushed through the meatus. As shown in the video, the ointment will protrude through the fistulas anywhere along the shaft. This technique can also be performed reversely as the ointment inserted from the fistulas will protrude from the meatus. For younger children under the age of 3, we exclusively perform this technique under anesthesia on the repair surgery day, whereas in toddlers we perform this technique in the office and once again under anesthesia right before the repair surgery.
This technique shows even tiny and multiple fistulas not detectable on physical examinations. We have used this technique in our clinic and have not missed any fistulas. The diameter of the protruded ointment in reverse fistulography is an indicator of the distal urethral diameter. Therefore, in case of narrow ointment diameter, distal urethral strictures should be suspected as correction of distal obstruction is an important determinant in the success rate of fistula repair surgery. CONCLUSION: We suggest this diagnostic technique as a safe, inexpensive, easy, office-based, feasible, and reproducible method. Negative urine culture is not required for this examination. Also, there is no need to insert contrast media as in retrograde urethrography or induce anesthesia as in cystoscopy. We believe this simple technique help urologists around the world to diagnose this common complication of hypospadias surgery without the need for special equipment.
尿道下裂是男性生殖道常见的先天性畸形。尿道下裂修复术后最常见的并发症是尿道皮肤瘘。据报道,其在全球的发病率高达35%。这些瘘管的诊断有时具有挑战性,尤其是对于微小和多发的瘘管。通常,家长会抱怨术后阴茎腹侧有尿液喷洒、滴漏或尿液呈单股流出。体格检查时尿道皮肤瘘并不总是可见。为了选择手术修复技术,确定瘘管位置及其周围皮肤状况非常重要。在修复手术前还应确定远端尿道的通畅情况和解剖结构。这就是为什么泌尿外科医生通常使用逆行尿道造影或膀胱镜检查来查找瘘管位置。然而,这些方法对儿童有其自身风险,且并不总是有效。有时注入的造影剂会堵塞一些瘘管,尤其是靠近龟头处的瘘管,从而妨碍诊断。我们介绍一种尿道下裂修复术后筛查尿道皮肤瘘的简便技术。
在该技术(视频1)中,握住阴茎根部,将抗生素软膏经尿道口插入,然后轻轻将软膏从尿道口推进。如视频所示,软膏会从阴茎体部任何位置的瘘管中突出。该技术也可反向操作,因为从瘘管插入的软膏会从尿道口突出。对于3岁以下的幼儿,我们仅在修复手术当天在麻醉下进行此操作,而对于学步儿童,我们在诊室进行此操作,并在修复手术前再次在麻醉下进行。
该技术能显示体格检查无法发现的微小和多发瘘管。我们已在诊所使用该技术,未漏诊任何瘘管。反向瘘管造影中突出软膏的直径可作为远端尿道直径的指标。因此,若软膏直径较窄,应怀疑远端尿道狭窄,因为纠正远端梗阻是瘘管修复手术成功率的重要决定因素。结论:我们建议将这种诊断技术作为一种安全、廉价、简便、基于诊室、可行且可重复的方法。该检查无需进行尿液培养阴性检查。此外,无需像逆行尿道造影那样注入造影剂,也无需像膀胱镜检查那样诱导麻醉。我们相信这种简单技术能帮助世界各地的泌尿外科医生诊断尿道下裂手术的这种常见并发症,而无需特殊设备。