Free dug concentrations in pregnancy: Bound to measure unbound?
作者信息
Schalkwijk Stein, Greupink Rick, Burger David
机构信息
Department of Pharmacy, Radboud Institute for Health Sciences (RIHS), Radboud University Medical Center, Nijmegen, The Netherlands.
Department of Pharmacology & Toxicology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.
出版信息
Br J Clin Pharmacol. 2017 Dec;83(12):2595-2598. doi: 10.1111/bcp.13432. Epub 2017 Oct 6.
Abstract
摘要
相似文献
1
Free dug concentrations in pregnancy: Bound to measure unbound?
Br J Clin Pharmacol. 2017 Dec;83(12):2595-2598. doi: 10.1111/bcp.13432. Epub 2017 Oct 6.
2
Phenytoin protein binding and dosage requirements during acute and convalescent phases following brain injury.
Ann Pharmacother. 1996 May;30(5):443-8. doi: 10.1177/106002809603000501.
3
Serum albumin reserve for bilirubin binding during pregnancy in healthy women.
Obstet Gynecol. 1989 Jan;73(1):93-6.
4
Interaction of beta-lactam antibiotics on bilirubin-albumin complex: comparison by three methods, total bilirubin, unbound bilirubin and erythrocyte-bound bilirubin.
Chemotherapy. 1990;36(2):91-7. doi: 10.1159/000238753.
5
First-derivative spectroscopic determination of binding characteristics of rifampicin to human albumin and serum.
J Pharm Sci. 1992 Mar;81(3):287-9. doi: 10.1002/jps.2600810319.
6
Plasma protein binding of quinine: binding to human serum albumin, alpha 1-acid glycoprotein and plasma from patients with malaria.
J Pharm Pharmacol. 1992 Oct;44(10):806-11. doi: 10.1111/j.2042-7158.1992.tb03210.x.
7
Unbound phenytoin plasma concentrations in patients comedicated with sodium valproate--the predictive value of plasma albumin concentration.
Br J Clin Pharmacol. 1989 Jun;27(6):843-9. doi: 10.1111/j.1365-2125.1989.tb03448.x.
8
Determination of unbound fraction of pazopanib in vitro and in cancer patients reveals albumin as the main binding site.
Invest New Drugs. 2016 Feb;34(1):41-8. doi: 10.1007/s10637-015-0304-9. Epub 2015 Nov 16.
9
Predicting Unbound Phenytoin Concentrations: Effects of Albumin Concentration and Kidney Dysfunction.
Pharmacotherapy. 2019 Jul;39(7):756-766. doi: 10.1002/phar.2273. Epub 2019 May 30.
10
Variability in teicoplanin protein binding and its prediction using serum albumin concentrations.
Ther Drug Monit. 2007 Aug;29(4):399-403. doi: 10.1097/FTD.0b013e3180690755.
引用本文的文献
1
Concentration-dependent blood binding: assessing implications through physiologically based Pharmacokinetic modeling of tacrolimus as a case example.
J Pharmacokinet Pharmacodyn. 2025 Sep 4;52(5):50. doi: 10.1007/s10928-025-09992-5.
2
Critical assessment of infants born to mothers with drug resistant tuberculosis.
EClinicalMedicine. 2024 Sep 5;76:102821. doi: 10.1016/j.eclinm.2024.102821. eCollection 2024 Oct.
3
Brief Report: Dolutegravir Plasma Protein Binding and Unbound Concentrations During Pregnancy and Postpartum.
J Acquir Immune Defic Syndr. 2023 Dec 1;94(4):332-336. doi: 10.1097/QAI.0000000000003281.
4
Best practices for the care of pregnant people living with TB.
Int J Tuberc Lung Dis. 2023 May 1;27(5):357-366. doi: 10.5588/ijtld.23.0031.
5
Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin-resistant tuberculosis.
Br J Clin Pharmacol. 2022 Aug;88(8):3548-3558. doi: 10.1111/bcp.15380. Epub 2022 May 26.
6
An update on the physiologic changes during pregnancy and their impact on drug pharmacokinetics and pharmacogenomics.
J Basic Clin Physiol Pharmacol. 2021 Dec 8;33(5):581-598. doi: 10.1515/jbcpp-2021-0312. eCollection 2022 Sep 1.
7
A population pharmacokinetics analysis assessing the exposure of raltegravir once-daily 1200 mg in pregnant women living with HIV.
CPT Pharmacometrics Syst Pharmacol. 2021 Feb;10(2):161-172. doi: 10.1002/psp4.12586. Epub 2021 Jan 25.
8
Drug-Drug Interactions with Antiretroviral Drugs in Pregnant Women Living with HIV: Are They Different from Non-Pregnant Individuals?
Clin Pharmacokinet. 2020 Oct;59(10):1217-1236. doi: 10.1007/s40262-020-00914-x.
9
Review article: direct-acting antivirals for the treatment of HCV during pregnancy and lactation - implications for maternal dosing, foetal exposure, and safety for mother and child.
Aliment Pharmacol Ther. 2019 Oct;50(7):738-750. doi: 10.1111/apt.15476. Epub 2019 Aug 25.
10
Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling.
J Antimicrob Chemother. 2019 May 1;74(5):1348-1356. doi: 10.1093/jac/dky567.
本文引用的文献
1
Antiretroviral unbound concentration during pregnancy: piece of interest in the puzzle?
J Antimicrob Chemother. 2017 Sep 1;72(9):2407-2409. doi: 10.1093/jac/dkx176.
2
Free and total plasma concentrations of elvitegravir/cobicistat during pregnancy and postpartum: a case report.
Br J Clin Pharmacol. 2017 Dec;83(12):2835-2838. doi: 10.1111/bcp.13310. Epub 2017 May 16.
3
Pharmacokinetics of Total and Unbound Etravirine in HIV-1-Infected Pregnant Women.
J Acquir Immune Defic Syndr. 2016 Nov 1;73(3):268-274. doi: 10.1097/QAI.0000000000001068.
4
Pharmacokinetics of total and unbound darunavir in HIV-1-infected pregnant women.
J Antimicrob Chemother. 2015 Feb;70(2):534-42. doi: 10.1093/jac/dku400. Epub 2014 Oct 17.
5
Earlier initiation of ART and further decline in mother-to-child HIV transmission rates, 2000-2011.
AIDS. 2014 Apr 24;28(7):1049-57. doi: 10.1097/QAD.0000000000000212.
6
The importance of plasma protein binding in drug discovery.
Expert Opin Drug Discov. 2007 Jan;2(1):51-64. doi: 10.1517/17460441.2.1.51.
7
Free and total plasma levels of lopinavir during pregnancy, at delivery and postpartum: implications for dosage adjustments in pregnant women.
Antivir Ther. 2013;18(2):171-82. doi: 10.3851/IMP2328. Epub 2012 Aug 22.
8
Anatomical, physiological and metabolic changes with gestational age during normal pregnancy: a database for parameters required in physiologically based pharmacokinetic modelling.
Clin Pharmacokinet. 2012 Jun 1;51(6):365-96. doi: 10.2165/11597440-000000000-00000.
9
Monitoring free drug concentrations: challenges.
Bioanalysis. 2011 Aug;3(15):1753-68. doi: 10.4155/bio.11.187.
10
Use of enhanced perinatal human immunodeficiency virus surveillance methods to assess antiretroviral use and perinatal human immunodeficiency virus transmission in the United States, 1999-2001.
Am J Obstet Gynecol. 2007 Sep;197(3 Suppl):S33-41. doi: 10.1016/j.ajog.2007.03.081.
Zotero 插件