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对缺铁性贫血孕妇采用总剂量输注法给予右旋糖酐铁(Imferon)的耐受性及反应评估。

Evaluation of tolerance of and response to iron dextran (Imferon) administered by total dose infusion to pregnant women with iron deficiency anemia.

作者信息

Kaisi M, Ngwalle E W, Runyoro D E, Rogers J

机构信息

Department of Obstetrics and Gynaecology, Muhimbili Medical Centre, Dar es Salaam, Tanzania.

出版信息

Int J Gynaecol Obstet. 1988 Apr;26(2):235-43. doi: 10.1016/0020-7292(88)90268-8.

Abstract

Six hundred twenty-three pregnant women with iron deficiency anemia received iron dextran Imferon by total dose infusion (TDI). Two dose levels were compared in respect of tolerance and hemoglobin response. The incidence of delayed reactions was significantly higher in the high dose group (P less than 0.01) but there was no significant difference in the incidence of reactions occurring during the infusion. These findings are discussed in relation to the hemoglobin response.

摘要

623名缺铁性贫血孕妇接受了右旋糖酐铁(Imferon)全剂量输注(TDI)。比较了两个剂量水平的耐受性和血红蛋白反应。高剂量组延迟反应的发生率显著更高(P<0.01),但输注期间反应的发生率没有显著差异。结合血红蛋白反应对这些发现进行了讨论。

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