Paul Siba Prosad, Sandhu Bhupinder Kaur
Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol, UK. Correspondence to: Dr Siba Prosad Paul, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK.
Indian Pediatr. 2017 Sep 15;54(9):742-745. doi: 10.1007/s13312-017-1166-3.
To document the frequency at diagnosis and evolution over time of inflammatory bowel disease-unclassified in children.
Analysis of case records (2004-2011) of patients diagnosed with inflammatory bowel disease-unclassified following upper-gastrointestinal endoscopy, ileocolonoscopy and small bowel imaging. Any subsequent diagnostic reclassification by 2016 was recorded.
344 children diagnosed as inflammatory bowel disease: 58% Crohn's disease, 34.5% ulcerative colitis, and 7.5% (n=26) inflammatory bowel disease-unclassified. 25/26 inflammatory bowel disease-unclassified patients were followed for 4.5-11.5 years. 17 of these patients needed endoscopic re-evaluation leading to changed diagnosis in ten (Crohn's disease 7, ulcerative colitis 3).
7.5% (25/344) of inflammatory bowel disease children had inflammatory bowel disease-unclassified at diagnosis; 10 (40%) evolved into Crohn's disease or ulcerative colitis.
记录儿童炎症性肠病未分类在诊断时的发生率及随时间的演变情况。
分析2004年至2011年经上消化道内镜检查、回结肠镜检查及小肠成像诊断为炎症性肠病未分类的患者的病例记录。记录截至2016年的任何后续诊断重新分类情况。
344名儿童被诊断为炎症性肠病：58%为克罗恩病，34.5%为溃疡性结肠炎，7.5%（n = 26）为炎症性肠病未分类。25/26例炎症性肠病未分类患者随访4.5至11.5年。其中17例患者需要内镜重新评估，导致10例诊断改变（克罗恩病7例，溃疡性结肠炎3例）。
7.5%（25/344）的炎症性肠病儿童在诊断时为炎症性肠病未分类；10例（40%）演变为克罗恩病或溃疡性结肠炎。
