Shah Pankaj B, James Saji, Elayaraja S
Department of Community Medicine, Sri Ramachandra Medical College and Research Institute, Sri. Ramachandra University, Ramachandra Nagar, Porur, Chennai, Tamil Nadu, India, 600116.
Cochrane Database Syst Rev. 2017 Oct 7;10(10):CD009196. doi: 10.1002/14651858.CD009196.pub4.
Febrile seizures can be classified as simple or complex. Complex febrile seizures are associated with fever that lasts longer than 15 minutes, occur more than once within 24 hours, and are confined to one side of the child's body. It is common in some countries for doctors to recommend an electroencephalograph (EEG) for children with complex febrile seizures. A limited evidence base is available to support the use of EEG and its timing after complex febrile seizures among children.
To assess the use of EEG and its timing after complex febrile seizures in children younger than five years of age.
For the latest update of this review, we searched the Cochrane Epilepsy Group Specialized Register (23 January 2017), the Cochrane Central Register of Controlled Trials (CENTRAL) via the Cochrane Register of Studies Online (CRSO, 23 January 2017), MEDLINE (Ovid, 23 January 2017), and ClinicalTrials.gov (23 January 2017). We applied no language restrictions.
All randomised controlled trials (RCTs) that examined the utility of an EEG and its timing after complex febrile seizures in children.
The review authors selected and retrieved the articles and independently assessed which articles should be included. Any disagreements were resolved by discussion and by consultation with the Cochrane Epilepsy Group. We applied standard methodological procedures expected by Cochrane.
Of 41 potentially eligible studies, no RCTs met the inclusion criteria.
AUTHORS' CONCLUSIONS: We found no RCTs as evidence to support or refute the use of EEG and its timing after complex febrile seizures among children. An RCT can be planned in such a way that participants are randomly assigned to the EEG group and to the non-EEG group with sufficient sample size. Since the last version of this review, we have found no new studies.
热性惊厥可分为简单型或复杂型。复杂型热性惊厥与持续超过15分钟的发热、24小时内发作不止一次以及局限于患儿身体一侧有关。在一些国家,医生通常会建议对患有复杂型热性惊厥的儿童进行脑电图(EEG)检查。目前支持在儿童复杂型热性惊厥后使用脑电图及其检查时机的证据有限。
评估5岁以下儿童复杂型热性惊厥后脑电图的使用情况及其检查时机。
为了对本综述进行最新更新,我们检索了Cochrane癫痫小组专业注册库(2017年1月23日)、通过Cochrane在线研究注册库(CRSO,2017年1月23日)检索Cochrane对照试验中心注册库(CENTRAL)、MEDLINE(Ovid,2017年1月23日)以及ClinicalTrials.gov(2017年1月23日)。我们未设语言限制。
所有检验脑电图在儿童复杂型热性惊厥后的效用及其检查时机的随机对照试验(RCT)。
综述作者筛选并检索文章,独立评估哪些文章应被纳入。任何分歧都通过讨论以及与Cochrane癫痫小组协商解决。我们采用了Cochrane预期的标准方法程序。
在41项可能符合条件的研究中,没有RCT符合纳入标准。
我们未找到RCT作为证据来支持或反驳在儿童复杂型热性惊厥后使用脑电图及其检查时机。可以设计一项RCT,将参与者随机分配到脑电图组和非脑电图组,且样本量充足。自本综述的上一版以来,我们未发现新的研究。