喂食被内生真菌（Acremonium coenophialum）感染的高羊茅种子对雌性大鼠怀孕和分娩的影响。

The effect of feeding tall fescue seed infected by Acremonium coenophialum on pregnancy and parturition in female rats.

Varney D R, Kappes C J, Jones S L, Newsome R, Siegel M R, Zavos P M

Department of Biological Sciences, Eastern Kentucky University, Richmond 40475.

Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;89(2):315-20. doi: 10.1016/0742-8413(88)90230-7.

Abstract

Female Sprague-Dawley rats (Rattus norvegicus) were randomly assigned to various dietary treatments containing: (1) 100% Purina rodent chow, ad libitum; (2) same as 1, but restricted to daily intake of 7; (3) 50% rodent chow (w/w) and 50% endophyte-free tall fescue (Festuca arundinacea) seed; (4) same as 3, but restricted to intake of 5; (5) 50% rodent chow, 25% endophyte-free tall fescue seed and 25% endophyte-infected (Acremonium coenophialum) tall fescue seed; (6) 50% rodent chow, 12.5% endophyte-free and 37.5% endophyte-infected tall fescue seed; and (7) 50% rodent chow and 50% endophyte infected tall fescue seed. 2. Average daily feed intakes and average daily weight gains decreased with higher levels of endophyte infected seed. 3. Frequency of litter production was affected by all endophyte-infected containing diets. 4. Conception was reduced only in dietary treatment (7). 5. Litter weights, number of pups per litter and weight per pup were proportionally reduced as higher levels of infected seed were incorporated in the ingested diets.

摘要

将雌性斯普拉格-道利大鼠（褐家鼠）随机分配至不同饮食处理组，饮食包含：（1）100%普瑞纳啮齿动物饲料，随意采食；（2）与（1）相同，但每日摄入量限制为7；（3）50%啮齿动物饲料（重量/重量）和50%无内生真菌的高羊茅种子；（4）与（3）相同，但摄入量限制为5；（5）50%啮齿动物饲料、25%无内生真菌的高羊茅种子和25%感染内生真菌（内生真菌）的高羊茅种子；（6）50%啮齿动物饲料、12.5%无内生真菌和37.5%感染内生真菌的高羊茅种子；以及（7）50%啮齿动物饲料和50%感染内生真菌的高羊茅种子。2. 随着感染内生真菌种子水平的提高，平均每日采食量和平均每日体重增加量下降。3.窝产频率受所有含感染内生真菌饲料的影响。4. 仅在饮食处理组（7）中受孕率降低。5. 随着摄入饲料中感染种子水平的提高，窝重、每窝幼崽数量和每只幼崽体重成比例降低。