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The ESCRT protein CHMP5 escorts αβ T cells through positive selection.

作者信息

Wu Glendon S, Bassing Craig H

机构信息

Immunology Graduate Group, Perelman School of Medicine, at the University of Pennsylvania, 19104, Philadelphia, PA, USA.

Divsion of Cancer Pathobiology, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Abramson Family Cancer Research Institute, Perelman School of Medicine, at the University of Pennsylvania, 19104, Philadelphia, PA, USA.

出版信息

Cell Mol Immunol. 2018 Jul;15(7):654-656. doi: 10.1038/cmi.2017.101. Epub 2017 Oct 9.

Abstract
摘要

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本文引用的文献

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Post-translational control of T cell development by the ESCRT protein CHMP5.
Nat Immunol. 2017 Jul;18(7):780-790. doi: 10.1038/ni.3764. Epub 2017 May 29.
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CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts.
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