Magliulo Giuseppe, de Vincentiis Marco, Iannella Giannicola, Ciofalo Andrea, Manno Alessandra, Pasquariello Benedetta, Angeletti Diletta, Pace Annalisa, Gulotta Giampiero, Polimeni Antonella
a 'Organi di Senso' Department , Sapienza University of Rome , Rome , Italy.
b Department of Oral and Maxillo Facial Sciences , Sapienza University of Rome , Rome , Italy.
Acta Otolaryngol. 2018 Feb;138(2):159-164. doi: 10.1080/00016489.2017.1385846. Epub 2017 Oct 9.
Investigate the presence of Eustachian Tube Dysfunction (ETD) in Obstructive sleep apnea (OSA) patients. Correlate the ET function and the severity of the sleep apnea syndrome. Correlate nasal resistance and nasal mucociliary clearance with the onset of ETD in these patients.
Forty patients affected by OSA were enrolled in our clinical prospective study. Thirty patients were also investigated as a control group. All of the analyzed subjects underwent ENT examination, anterior rhinomanometry and test for mucociliary transport time. To evaluate Eustachian tube function the Eustachian tube score-7 (ETS-7) were employed.
Twenty percent of the patients with a diagnosis of OSA had a diagnosis of ETD (ETS-7 ≤ 7) with a statistical difference with control group (p = .03). No differences regarding ETD in OSA sub-groups were found.
This study showed that ET blockage or delayed openings were found in most adult patients with OSA when evaluated by a sensible score as the ETS-7. Our data suggest that an evaluation of the Eustachian tube function should be performed in patients suffering from obstructive sleep apnea syndrome.
调查阻塞性睡眠呼吸暂停（OSA）患者中咽鼓管功能障碍（ETD）的存在情况。将咽鼓管功能与睡眠呼吸暂停综合征的严重程度相关联。将这些患者的鼻阻力和鼻黏液纤毛清除功能与ETD的发病情况相关联。
40例受OSA影响的患者纳入我们的临床前瞻性研究。还对30例患者作为对照组进行了调查。所有分析对象均接受耳鼻喉科检查、前鼻测压和黏液纤毛运输时间测试。为评估咽鼓管功能，采用了咽鼓管评分-7（ETS-7）。
诊断为OSA的患者中有20%被诊断为ETD（ETS-7≤7），与对照组有统计学差异（p = 0.03）。在OSA亚组中未发现关于ETD的差异。
本研究表明，当通过如ETS-7这样的敏感评分进行评估时，大多数成年OSA患者存在咽鼓管阻塞或开放延迟。我们的数据表明，对于患有阻塞性睡眠呼吸暂停综合征的患者，应进行咽鼓管功能评估。
