a Yong Loo Lin School of Medicine , National University of Singapore , Singapore , Singapore.
b National Healthcare Group Eye Institute , Tan Tock Seng Hospital , Singapore , Singapore.
Ocul Immunol Inflamm. 2019;27(1):89-98. doi: 10.1080/09273948.2017.1358377. Epub 2017 Oct 9.
To report the pattern of posterior and panuveitis at a tertiary referral center in Singapore.
Subgroup retrospective analysis of 334 new posterior and panuveitis cases, from the Ocular Autoimmune Systemic Inflammatory Infectious Study (OASIS) database. Descriptive analysis was performed and visual outcome and complications were reported.
The etiology for posterior uveitis and panuveitis was infectious in 162 patients (48.5%), non-infectious in 144 patients (43.1%), and idiopathic in 28 patients (8.4%). More patients with bilateral disease had a non-infectious etiology (n = 82, 50.9%) (p = 0.012). The most common complication was epiretinal membrane (n = 20, 12.3%) for the infectious group and cystoid macular edema (n = 12, 8.3%) for the non-infectious group.
The proportion of etiologies in our cohort varies from other studies. Understanding the variations and demographic associations allows the diagnosis and management of posterior and panuveitis to be further improved.
报告在新加坡一家三级转诊中心发生的后葡萄膜炎和全葡萄膜炎的模式。
对 334 例新的后葡萄膜炎和全葡萄膜炎病例进行亚组回顾性分析，这些病例来自眼自身免疫性系统性炎症感染研究（OASIS）数据库。进行描述性分析，并报告视力结果和并发症。
后葡萄膜炎和全葡萄膜炎的病因在 162 例患者（48.5%）中为感染性，在 144 例患者（43.1%）中为非感染性，在 28 例患者（8.4%）中为特发性。双侧疾病患者中，非感染性病因更为常见（n=82，50.9%）（p=0.012）。感染组最常见的并发症是视网膜前膜（n=20，12.3%），非感染组最常见的并发症是黄斑囊样水肿（n=12，8.3%）。
我们队列中的病因比例与其他研究不同。了解这些差异和人口统计学关联，可以进一步改善后葡萄膜炎和全葡萄膜炎的诊断和管理。
