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本文引用的文献

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Adolescent cannabis use, change in neurocognitive function, and high-school graduation: A longitudinal study from early adolescence to young adulthood.青少年大麻使用、神经认知功能变化与高中毕业:一项从青春期早期到青年期的纵向研究。
Dev Psychopathol. 2017 Oct;29(4):1253-1266. doi: 10.1017/S0954579416001280. Epub 2016 Dec 29.
2
The design of medical marijuana laws and adolescent use and heavy use of marijuana: Analysis of 45 states from 1991 to 2011.医用大麻法律的设计与青少年使用及大量使用大麻的情况:对1991年至2011年45个州的分析
Drug Alcohol Depend. 2017 Jan 1;170:1-8. doi: 10.1016/j.drugalcdep.2016.10.028. Epub 2016 Nov 4.
3
Underage Drinking: A Review of Trends and Prevention Strategies.未成年人饮酒:趋势与预防策略综述
Am J Prev Med. 2016 Oct;51(4 Suppl 2):S148-57. doi: 10.1016/j.amepre.2016.05.020. Epub 2016 Jul 28.
4
The availability of medical marijuana dispensary and adolescent marijuana use.医用大麻药房的可及性与青少年大麻使用情况。
Prev Med. 2016 Oct;91:1-7. doi: 10.1016/j.ypmed.2016.07.015. Epub 2016 Jul 25.
5
Capturing Heterogeneity in Medical Marijuana Policies: A Taxonomy of Regulatory Regimes Across the United States.把握医用大麻政策的异质性:美国监管制度分类法
Subst Use Misuse. 2016 Jul 28;51(9):1174-84. doi: 10.3109/10826084.2016.1160932. Epub 2016 May 18.
6
Pediatric Concerns Due to Expanded Cannabis Use: Unintended Consequences of Legalization.大麻使用扩大引发的儿科问题:合法化的意外后果
J Med Toxicol. 2017 Mar;13(1):99-105. doi: 10.1007/s13181-016-0552-x. Epub 2016 May 2.
7
Prevalence of marijuana use does not differentially increase among youth after states pass medical marijuana laws: Commentary on and reanalysis of US National Survey on Drug Use in Households data 2002-2011.在各州通过医用大麻法律后,青少年中使用大麻的流行率并未出现差异增长:对2002 - 2011年美国全国药物使用家庭调查数据的评论与重新分析
Int J Drug Policy. 2016 Mar;29:9-13. doi: 10.1016/j.drugpo.2016.01.015. Epub 2016 Feb 1.
8
Impacts of Changing Marijuana Policies on Alcohol Use in the United States.美国大麻政策变化对酒精使用的影响。
Alcohol Clin Exp Res. 2016 Jan;40(1):33-46. doi: 10.1111/acer.12942. Epub 2015 Dec 21.
9
Medical marijuana laws and adolescent marijuana use in the USA from 1991 to 2014: results from annual, repeated cross-sectional surveys.1991年至2014年美国医用大麻法律与青少年大麻使用情况:年度重复横断面调查结果
Lancet Psychiatry. 2015 Jul;2(7):601-8. doi: 10.1016/S2215-0366(15)00217-5. Epub 2015 Jun 15.
10
The effect of medical cannabis laws on juvenile cannabis use.医用大麻法律对青少年大麻使用的影响。
Int J Drug Policy. 2016 Jan;27:82-8. doi: 10.1016/j.drugpo.2015.05.018. Epub 2015 Jun 6.

州级医用大麻法律的异质性与青少年近期酒精和大麻使用:对 1991-2011 年间 45 个州的分析。

Heterogeneity of state medical marijuana laws and adolescent recent use of alcohol and marijuana: Analysis of 45 states, 1991-2011.

机构信息

a Department of Mental Health , Johns Hopkins Bloomberg School of Public Health, Baltimore Maryland , USA.

b The Center for Adolescent Substance Abuse Research (CeASAR), Boston Children's Hospital , Boston , Massachusetts , USA.

出版信息

Subst Abus. 2018;39(2):247-254. doi: 10.1080/08897077.2017.1389801. Epub 2017 Nov 13.

DOI:10.1080/08897077.2017.1389801
PMID:28991522
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5891387/
Abstract

OBJECTIVE

To assess associations between enactment of state medical marijuana laws (MMLs), MML restrictiveness, and past-30-day youth alcohol use overall, and in relation to marijuana use.

METHOD

This quasi-experimental difference-in-difference designed study used state-level Youth Risk Behavior Survey data of 9th-12th grade students in 45 states from 1991-2011 (N D 715,014). We conducted bivariate (unadjusted) and multivariable (adjusted for state, year, individual characteristics) logistic regression analyses to examine the effect of MML enactment (yes/no) and less restrictive vs. more restrictive MMLs on five varying measures of past 30-day alcohol use (i.e., any use or binge) and alcohol and marijuana use behaviors.

RESULTS

In the final adjusted analyses, MML enactment was associated with lower odds of adolescent past 30-day (1) alcohol use (OR D 0.92, [0.87, 0.97], p < .01) and (2) use of both alcohol and marijuana (OR D 0.93, [0.87, 0.99], p < .05). States with less restrictive MMLs had lower odds of past 30-day (1) alcohol use (OR D 0.94, [0.92, 0.97], p < .001), (2) binge drinking (OR D 0.96, [0.93, 0.97], p < .05), (3) alcohol use without any marijuana use (OR D 0.96, [0.93, 0.99], p < .01), and (4) use of both alcohol and marijuana (OR D 0.96, [0.92, 0.99], p < .05).

CONCLUSIONS

This study found that enactment of any MML, and of less restrictive MMLs, was associated with lower odds of past 30-day adolescent alcohol use among adolescents. With continued change in state marijuana laws, it is important to monitor the effect of their enactment and implementation, as well as their specific provisions (e.g. dispensaries, home cultivation), which may differentially affect adolescent behaviors.

摘要

目的

评估州医疗大麻法(MML)的颁布、MML 的限制程度以及过去 30 天青少年饮酒总体情况之间的关联,以及与大麻使用的关联。

方法

本研究采用准实验性差异-差异设计,使用 1991-2011 年间来自 45 个州的 9 至 12 年级学生的州级青少年风险行为调查数据(N=715014)。我们进行了双变量(未调整)和多变量(按州、年、个体特征调整)逻辑回归分析,以检验 MML 颁布(是/否)和限制较少与限制较多的 MML 对过去 30 天五种不同的酒精使用情况(即任何使用或狂饮)以及酒精和大麻使用行为的影响。

结果

在最终的调整分析中,MML 的颁布与青少年过去 30 天(1)酒精使用的几率降低相关(OR=0.92,[0.87,0.97],p<.01)和(2)同时使用酒精和大麻的几率降低相关(OR=0.93,[0.87,0.99],p<.05)。限制较少的 MML 的州过去 30 天(1)酒精使用的几率降低(OR=0.94,[0.92,0.97],p<.001),(2)狂饮的几率降低(OR=0.96,[0.93,0.97],p<.05),(3)没有使用任何大麻的酒精使用几率降低(OR=0.96,[0.93,0.99],p<.01),以及(4)同时使用酒精和大麻的几率降低(OR=0.96,[0.92,0.99],p<.05)。

结论

本研究发现,任何 MML 的颁布以及限制较少的 MML 的颁布与青少年过去 30 天的酒精使用几率降低相关。随着州大麻法的持续变化,监测其颁布和实施的效果以及其具体规定(例如,药房,家庭种植)非常重要,这些规定可能会对青少年行为产生不同的影响。