a Department of Mental Health , Johns Hopkins Bloomberg School of Public Health, Baltimore Maryland , USA.
b The Center for Adolescent Substance Abuse Research (CeASAR), Boston Children's Hospital , Boston , Massachusetts , USA.
Subst Abus. 2018;39(2):247-254. doi: 10.1080/08897077.2017.1389801. Epub 2017 Nov 13.
To assess associations between enactment of state medical marijuana laws (MMLs), MML restrictiveness, and past-30-day youth alcohol use overall, and in relation to marijuana use.
This quasi-experimental difference-in-difference designed study used state-level Youth Risk Behavior Survey data of 9th-12th grade students in 45 states from 1991-2011 (N D 715,014). We conducted bivariate (unadjusted) and multivariable (adjusted for state, year, individual characteristics) logistic regression analyses to examine the effect of MML enactment (yes/no) and less restrictive vs. more restrictive MMLs on five varying measures of past 30-day alcohol use (i.e., any use or binge) and alcohol and marijuana use behaviors.
In the final adjusted analyses, MML enactment was associated with lower odds of adolescent past 30-day (1) alcohol use (OR D 0.92, [0.87, 0.97], p < .01) and (2) use of both alcohol and marijuana (OR D 0.93, [0.87, 0.99], p < .05). States with less restrictive MMLs had lower odds of past 30-day (1) alcohol use (OR D 0.94, [0.92, 0.97], p < .001), (2) binge drinking (OR D 0.96, [0.93, 0.97], p < .05), (3) alcohol use without any marijuana use (OR D 0.96, [0.93, 0.99], p < .01), and (4) use of both alcohol and marijuana (OR D 0.96, [0.92, 0.99], p < .05).
This study found that enactment of any MML, and of less restrictive MMLs, was associated with lower odds of past 30-day adolescent alcohol use among adolescents. With continued change in state marijuana laws, it is important to monitor the effect of their enactment and implementation, as well as their specific provisions (e.g. dispensaries, home cultivation), which may differentially affect adolescent behaviors.
评估州医疗大麻法(MML)的颁布、MML 的限制程度以及过去 30 天青少年饮酒总体情况之间的关联,以及与大麻使用的关联。
本研究采用准实验性差异-差异设计,使用 1991-2011 年间来自 45 个州的 9 至 12 年级学生的州级青少年风险行为调查数据(N=715014)。我们进行了双变量(未调整)和多变量(按州、年、个体特征调整)逻辑回归分析,以检验 MML 颁布(是/否)和限制较少与限制较多的 MML 对过去 30 天五种不同的酒精使用情况(即任何使用或狂饮)以及酒精和大麻使用行为的影响。
在最终的调整分析中,MML 的颁布与青少年过去 30 天(1)酒精使用的几率降低相关(OR=0.92,[0.87,0.97],p<.01)和(2)同时使用酒精和大麻的几率降低相关(OR=0.93,[0.87,0.99],p<.05)。限制较少的 MML 的州过去 30 天(1)酒精使用的几率降低(OR=0.94,[0.92,0.97],p<.001),(2)狂饮的几率降低(OR=0.96,[0.93,0.97],p<.05),(3)没有使用任何大麻的酒精使用几率降低(OR=0.96,[0.93,0.99],p<.01),以及(4)同时使用酒精和大麻的几率降低(OR=0.96,[0.92,0.99],p<.05)。
本研究发现,任何 MML 的颁布以及限制较少的 MML 的颁布与青少年过去 30 天的酒精使用几率降低相关。随着州大麻法的持续变化,监测其颁布和实施的效果以及其具体规定(例如,药房,家庭种植)非常重要,这些规定可能会对青少年行为产生不同的影响。