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儿童白内障手术中囊袋内人工晶状体植入与后囊膜截开术后效果比较。

Postoperative outcomes of intraocular lens implantation in the bag versus posterior optic capture in pediatric cataract surgery.

机构信息

From the Iladevi Cataract & IOL Research Centre (A.B. Vasavada, V. Vasavada, Shah, V.A. Vasavada, S.A. Vasavada, Srivastava, Sudhalkar), Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.

From the Iladevi Cataract & IOL Research Centre (A.B. Vasavada, V. Vasavada, Shah, V.A. Vasavada, S.A. Vasavada, Srivastava, Sudhalkar), Ahmedabad, India; Storm Eye Institute (Trivedi), Medical University of South Carolina, Charleston, South Carolina, USA.

出版信息

J Cataract Refract Surg. 2017 Sep;43(9):1177-1183. doi: 10.1016/j.jcrs.2017.07.022.

Abstract

PURPOSE

To compare complications in children up to 4 years old having cataract surgery with intraocular lens (IOL) implantation using 2 techniques: in-the-bag IOL with anterior vitrectomy or optic capture of IOL with no anterior vitrectomy.

SETTING

Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

DESIGN

Prospective randomized control clinical trial.

METHODS

The study included children having cataract surgery with IOL implantation. Patients were randomized to Group 1 (in-the-bag 3-piece hydrophobic acrylic IOL [Acrysof MA60AC] with anterior vitrectomy) or Group 2 (optic capture of the same IOL without anterior vitrectomy). Intraoperative complications were documented. Postoperative visual axis obscuration (VAO), glaucoma, cell deposits on the IOL, and posterior synechiae were compared at 1, 3, 6, and 12 months.

RESULTS

The study comprised 61 children (61 eyes). The mean ages were 14.8 months ±11.47 (SD) in Group 1 (n = 30) and 18.2 ± 11.47 months in Group 2 (n = 31). Overall, only 1 eye in Group 1 developed a VAO requiring membranectomy 4 months postoperatively, and 2 eyes in Group 1 developed glaucoma over 12 months (P = .49). Intraocular lens cell deposits and posterior synechiae were comparable between groups. The IOL could not be captured in 5 eyes (16.1%); no complications occurred in these eyes.

CONCLUSIONS

Optic capture of 3-piece hydrophobic acrylic IOLs could be achieved in most eyes. The VAO, glaucoma, and inflammation were comparable 12 months postoperatively. Thus, optic capture of an IOL is an alternative surgical technique that can be used to avoid vitrectomy, even in children younger than 4 years.

摘要

目的

比较两种手术方法(带襻人工晶状体[Acrysof MA60AC]囊袋内植入联合前段玻璃体切除术与无前段玻璃体切除术的人工晶状体光学襻固定)治疗 4 岁以下儿童白内障并植入人工晶状体的术后并发症。

设置

印度艾哈迈达巴德 Iladevi 白内障与人工晶状体研究中心。

设计

前瞻性随机对照临床试验。

方法

本研究纳入了行白内障手术并植入人工晶状体的儿童患者。患者被随机分为 1 组(带襻人工晶状体囊袋内植入联合前段玻璃体切除术)或 2 组(相同的人工晶状体光学襻固定联合无前段玻璃体切除术)。记录术中并发症。术后 1、3、6 和 12 个月时比较视轴遮挡、青光眼、人工晶状体上细胞沉积和后发性粘连的发生情况。

结果

本研究共纳入 61 例(61 只眼)患儿。1 组(n=30)平均年龄为 14.8 个月±11.47(标准差),2 组(n=31)平均年龄为 18.2 个月±11.47 个月。总体而言,1 组仅 1 只眼术后 4 个月发生需要行膜切除术的视轴遮挡,1 组有 2 只眼在 12 个月内发生青光眼(P=.49)。两组间人工晶状体细胞沉积和后发性粘连的发生率相似。5 只眼(16.1%)未能成功固定人工晶状体,这些眼中无并发症发生。

结论

大多数情况下可成功完成 3 件式疏水性丙烯酸人工晶状体的光学襻固定。术后 12 个月时,视轴遮挡、青光眼和炎症无显著差异。因此,人工晶状体光学襻固定是一种替代手术技术,可以避免玻璃体切除术,即使在 4 岁以下儿童中也可以使用。

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