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先天性白内障手术中无玻璃体切割的后房型人工晶状体后囊捕获与前玻璃体切割的囊内人工晶状体植入的比较:一项随机前瞻性研究。

Comparison of posterior optic capture of intraocular lens without vitrectomy vs endocapsular implantation with anterior vitrectomy in congenital cataract surgery: A randomized prospective study.

机构信息

Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Ophthalmol. 2020 Jan;68(1):84-88. doi: 10.4103/ijo.IJO_522_19.

DOI:10.4103/ijo.IJO_522_19
PMID:31856476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6951169/
Abstract

PURPOSE

To compare surgical outcome of two procedures in pediatric cataract surgery.

METHODS

Prospective randomised interventional study. Consecutive patients with bilateral congenital cataract who were operated during January 2016 to October 2016 at a tertiary care referral institute were included. One eye of all patients underwent Intraocular lens (IOL) implantation with optic capture through a primary posterior continuous curvilinear capsulorhexis (PPC) without vitrectomy while in the other eye endocapsular IOL implantation was performed along with PPC and anterior vitrectomy. Intraoperative challenges and postoperative complications were noted.

RESULTS

15/18 children who fulfilled the inclusion criteria were included for follow up analysis. Mean age at the time of surgery was 21 ± 14.7 months. At a mean follow up of 25.69 ± 1.06 months; all eyes in both groups maintained a clinically centred IOL with clear visual axis. One patient with endocapsular IOL implantation developed anterior capsular phimosis. The rate of fibrinous complications (IOL deposits and synechiae) were more in the eyes with IOL in the bag (6 eyes) vs eyes where posterior optic capture was done (1 eye); P = 0.039.

CONCLUSION

Posterior optic capture is a safer alternative to conventional pediatric cataract surgery in terms of inflammatory sequelae and lens epithelial cell proliferation. However the two methods work equally well in preventing visual axis obscuration over a long follow-up.

摘要

目的

比较两种手术方法在小儿白内障手术中的疗效。

方法

前瞻性随机对照研究。纳入 2016 年 1 月至 2016 年 10 月在一家三级转诊医院接受双侧先天性白内障手术的连续患者。所有患者的一只眼均通过无玻璃体切割的原发性后连续环行撕囊(PPC)行人工晶状体(IOL)植入和光学捕获,而另一只眼则行囊内 IOL 植入和 PPC 及前玻璃体切割术。记录术中的挑战和术后并发症。

结果

18 名符合纳入标准的儿童中有 15 名接受了随访分析。手术时的平均年龄为 21 ± 14.7 个月。平均随访 25.69 ± 1.06 个月后,两组所有眼的 IOL 均保持在临床中心位置,视觉轴清晰。1 名行囊内 IOL 植入的患者发生了前囊膜纤维性收缩。后囊光学捕获眼(1 眼)的 IOL 沉积物和粘连等纤维性并发症发生率(6 眼)明显低于囊内 IOL 植入眼(P = 0.039)。

结论

在炎症后遗症和晶状体上皮细胞增殖方面,后囊光学捕获是一种比传统小儿白内障手术更安全的选择。然而,这两种方法在防止长期随访中视觉轴遮挡方面同样有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8941/6951169/ef18f84d4613/IJO-68-84-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8941/6951169/ef18f84d4613/IJO-68-84-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8941/6951169/ef18f84d4613/IJO-68-84-g001.jpg

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Intraocular lens implantation in children with unilateral congenital cataract in the first 4 years of life.4岁前单侧先天性白内障患儿的人工晶状体植入术。
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