Danforth R A, Baughman R A
Oral Surg Oral Med Oral Pathol. 1979 Sep;48(3):231-6. doi: 10.1016/0030-4220(79)90009-4.
It has been reported that epithelial nests associated with sensory nerve fibers may simulate perineural invasion and pose a potential diagnostic problem for surgical pathologists working on frozen tissue specimens from patients with oral cancer. The epithelial structures are not neoplastic, and no known pathologic condition has been associated with them. They are believed to be those structures described scantily in the English literature as Chievitz's organ. The fact that the epithelial nests lie near the plane of injection for the inferior alveolar nerve should be of special interest to dentists, especially oral surgeons and pathologists. Controversy exists as to the exact nature of Chievitz's organ, but the potential hazard of misdiagnosis exists nonetheless. This study of cadaver and autopsy material reaffirms the existence of the epithelial rests and outlines a simple technique for locating them.
据报道，与感觉神经纤维相关的上皮巢可能会模拟神经周围浸润，给处理口腔癌患者冰冻组织标本的外科病理学家带来潜在的诊断难题。这些上皮结构并非肿瘤性的，且尚无已知的病理状况与之相关。它们被认为是英文文献中鲜有描述的被称为奇维茨器官的结构。上皮巢位于下牙槽神经注射平面附近这一事实，应引起牙医尤其是口腔外科医生和病理学家的特别关注。关于奇维茨器官的确切性质存在争议，但误诊的潜在风险依然存在。这项对尸体和尸检材料的研究再次证实了上皮剩余的存在，并概述了一种定位它们的简单技术。
