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中国不同糖尿病进展阶段老年人群的空腹血清甘油三酯水平。

The fasting serum triglyceride levels of elderly population with different progression stages of diabetes mellitus in China.

机构信息

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, No. 29, Nanwei Road, Peking 100050, China.

National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, No. 29, Nanwei Road, Peking 100050, China.

出版信息

J Diabetes Complications. 2017 Dec;31(12):1641-1647. doi: 10.1016/j.jdiacomp.2017.08.011. Epub 2017 Aug 26.

Abstract

AIMS

This cross-sectional study aimed to investigate triglyceride level among Chinese elderly population with different diabetic progressions and related factors of triglyceride.

METHODS

Study participants (≥65years) were recruited from a nationwide cross-sectional surveillance and were divided into four subgroups according to diabetic progression. Their information was obtained via questionnaire and physical examination. Their lipids in fasting serum samples were analyzed.

RESULTS

The serum triglyceride levels (mmol/L, mean±SD) were 1.3±0.8 (subgroup of no prediabetes and no DM), 1.5±1.0 (subgroup of prediabetes), 1.6±1.1 (subgroup of newly diagnosed DM) and 1.7±1.1 (subgroup of previously diagnosed DM), respectively. Only one female participant had a higher triglyceride than upper limit for prevention of acute pancreatitis (11.0mmol/L). However, 23.1% of participants and 34.8% of DM participants had higher triglyceride than upper limit for prevention of cardiovascular diseases (1.7mmol/L). Triglyceride level was positively correlated with diabetic progression (r=0.17, p<0.01). Age, gender, waist-to-height ratio (rather than BMI), systolic pressure, serum total cholesterol and HDL-C levels were statistically correlated with triglyceride level for total participants (R=0.39, p<0.01).

CONCLUSIONS

Aggravation of serum triglyceride level was related to diabetic progression in Chinese elderly population. Triglyceride control was unsatisfactory in Chinese elderly population, especially in elderly population with DM.

摘要

目的

本横断面研究旨在探讨不同糖尿病进展阶段的中国老年人群的甘油三酯水平及其相关影响因素。

方法

研究对象(≥65 岁)来自全国性的横断面监测,根据糖尿病进展情况分为四组亚组。通过问卷调查和体格检查获取其信息,检测空腹血清样本中的血脂。

结果

血清甘油三酯水平(mmol/L,均值±标准差)分别为 1.3±0.8(无糖尿病前期和无糖尿病组)、1.5±1.0(糖尿病前期组)、1.6±1.1(新诊断糖尿病组)和 1.7±1.1(既往诊断糖尿病组)。仅有 1 名女性参与者的甘油三酯高于急性胰腺炎预防的上限(11.0mmol/L)。然而,23.1%的参与者和 34.8%的糖尿病患者的甘油三酯高于心血管疾病预防的上限(1.7mmol/L)。甘油三酯水平与糖尿病进展呈正相关(r=0.17,p<0.01)。对于总人群,年龄、性别、腰高比(而非 BMI)、收缩压、血清总胆固醇和高密度脂蛋白胆固醇水平与甘油三酯水平呈统计学相关(R=0.39,p<0.01)。

结论

中国老年人群的血清甘油三酯水平随着糖尿病的进展而恶化。中国老年人群的甘油三酯控制不理想,尤其是在老年糖尿病患者中。

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