Diec Jennie, Naduvilath Thomas, Tilia Daniel, Papas Eric B, Lazon de la Jara Percy
Brien Holden Vision Institute, Sydney, Australia.
Brien Holden Vision Institute, Sydney, Australia; School of Optometry and Vision Science, University of New South Wales, Australia.
Cont Lens Anterior Eye. 2017 Dec;40(6):367-381. doi: 10.1016/j.clae.2017.09.016. Epub 2017 Oct 6.
To describe a ranked symptoms scale (RSS) discriminating subjective responses in contact lens (CL) wear in various situations.
Forty experienced clinical trial participants were interviewed for their perceptions of ocular comfort scales, resulting in a numerical RSS. For further evaluation, 20 CL wearers enrolled into a prospective, randomised, crossover trial. Two silicone-hydrogel CLs and a lens care solution (LCS) [Combinations A & B] were selected based on prior performance identifying best/worst combinations for end-of-day comfort. The RSS and a numerical rating scale (NRS) were administered at two time-points (insertion/removal) on alternating days for 6 days.
Both NRS and RSS showed acceptable internal consistency for comfort, vision and handling (Cronbach alpha=0.71 for both scales) and similar repeatability for comfort and handling (coefficients-of-repeatability within 0.1 and 0.2 units, respectively, for each scale). The NRS and RSS discriminated differences between combinations for comfort (p≤0.031) and vision (p≤0.026) at both time-points. Additionally, the RSS showed lens/edge awareness influenced discomfort the most, ranking higher at insertion (p=0.038) and higher for Combination-B at both time-points (p≤0.002). Symptoms of dryness and tired eyes increased for both combinations at removal (p<0.02). The RSS also showed haziness and blurred distance vision influenced vision dissatisfaction with Combination-B at lens removal (p≤0.038) while eye strain/headache increased for both combinations by time of removal (p≤0.013).
The RSS is able to discriminate subjective responses between combinations and time-of-day. The RSS's ability to rank symptoms may be a useful tool in understanding perceptions of discomfort or dissatisfaction with CL wear.
描述一种分级症状量表（RSS），用于区分在各种情况下佩戴隐形眼镜（CL）时的主观反应。
对40名有经验的临床试验参与者进行访谈，了解他们对眼部舒适度量表的看法，从而得出一个数值化的RSS。为了进一步评估，20名隐形眼镜佩戴者参加了一项前瞻性、随机、交叉试验。根据之前确定的日间舒适度最佳/最差组合的表现，选择了两种硅水凝胶隐形眼镜和一种护理液（组合A和B）。在6天内，交替日的两个时间点（插入/取出时）使用RSS和数值评定量表（NRS）。
NRS和RSS在舒适度、视力和操作方面均显示出可接受的内部一致性（两种量表的Cronbach α系数均为0.71），在舒适度和操作方面具有相似的重复性（每种量表的重复性系数分别在0.1和0.2单位以内）。NRS和RSS在两个时间点均能区分组合之间在舒适度（p≤0.031）和视力（p≤0.026）方面的差异。此外，RSS显示镜片/边缘感知对不适感的影响最大，在插入时排名更高（p = 0.038），在两个时间点组合B的排名均更高（p≤0.002）。两种组合在取出时干眼和眼疲劳症状均增加（p<0.02）。RSS还显示，在取出镜片时，模糊和远距离视力模糊会影响对组合B的视力满意度（p≤0.038），而在取出时两种组合的眼疲劳/头痛症状均增加（p≤0.013）。
RSS能够区分不同组合和不同时间段的主观反应。RSS对症状进行分级的能力可能是理解佩戴隐形眼镜时的不适感或不满看法的有用工具。
