Bercu B B, Diamond F B
Department of Pediatrics, University of South Florida College of Medicine, St. Petersburg.
Pediatrician. 1987;14(3):94-108.
The regulation of human growth hormone secretion is complex involving both a hypothalamic stimulating and inhibiting hormone. These neurohormones are further regulated by neurotransmitters. Abnormalities in growth hormone secretion may occur in neurologic, psychiatric and metabolic disorders not related to short stature. In addition, the diagnosis of deficiency states of growth hormone secretion can often be very difficult. Guidelines for the work-up of short children are given.
人类生长激素分泌的调节很复杂，涉及下丘脑的促激素和抑制激素。这些神经激素进一步受神经递质调节。生长激素分泌异常可能发生在与身材矮小无关的神经、精神和代谢紊乱中。此外，生长激素分泌缺乏状态的诊断往往非常困难。文中给出了对矮小儿童检查的指导原则。
