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一名8个月大未完全接种疫苗的婴儿患百日咳,表现为反复咳嗽和喘息。

Pertussis manifesting as recurrent cough and wheezing in an incompletely vaccinated 8-month-old infant.

作者信息

Poddighe Dimitri, Nedbal Marco Giuseppe, Mastricci Nunzia, Bruni Paola

机构信息

Department of Pediatrics, ASST Melegnano e Martesana, Vizzolo Predabissi, Italy.

Department of Pediatrics, Univesità degli Studi di Pavia, Pavia, Italy.

出版信息

BMJ Case Rep. 2017 Oct 9;2017:bcr-2017-221562. doi: 10.1136/bcr-2017-221562.

DOI:10.1136/bcr-2017-221562
PMID:28993360
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5652862/
Abstract

Pertussis is an acute respiratory illness caused by , showing a re-emergence in developed countries. However, it is probably under-recognised and, as a consequence, its burden is underestimated. Here, we report the clinical case of an infant diagnosed with pertussis, despite a regular schedule of vaccination, thanks to a careful clinical evaluation, including personal and family history. In addition to pointing the attention on a precocious diagnosis of atypical cases of pertussis, this case report further raised the issue of modifying and/or implementing the immunisation strategy, considering the ongoing changes of social (eg, immigration) and sanitary (eg, vaccine coverage) background in Italy and all over the Europe.

摘要

百日咳是一种由[病原体未给出]引起的急性呼吸道疾病,在发达国家有再度流行的趋势。然而,它可能未得到充分认识,因此其负担被低估。在此,我们报告一例尽管按常规程序接种了疫苗,但仍被诊断为百日咳的婴儿临床病例,这得益于包括个人史和家族史在内的仔细临床评估。除了提醒注意百日咳非典型病例的早熟诊断外,本病例报告还进一步提出了修改和/或实施免疫策略的问题,考虑到意大利及整个欧洲社会(如移民)和卫生(如疫苗接种覆盖率)背景的持续变化。

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J Am Board Fam Med. 2017 Sep-Oct;30(5):681. doi: 10.3122/jabfm.2017.05.170221.
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Clinical Diagnosis of Bordetella Pertussis Infection: A Systematic Review.百日咳博德特氏菌感染的临床诊断:一项系统评价
J Am Board Fam Med. 2017 May-Jun;30(3):308-319. doi: 10.3122/jabfm.2017.03.160330.
3
Maternal pertussis immunisation: clinical gains and epidemiological legacy.孕产妇百日咳免疫接种:临床获益与流行病学影响
Euro Surveill. 2017 Apr 13;22(15). doi: 10.2807/1560-7917.ES.2017.22.15.30510.
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Postnatal cytomegalovirus infection in an infant with congenital thrombocytopenia: how it can support or mislead the diagnosis of Wiskott-Aldrich syndrome.一名先天性血小板减少症婴儿的产后巨细胞病毒感染:它如何支持或误导维斯科特-奥尔德里奇综合征的诊断。
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