Dilsaver S C, Alessi N E
Department of Psychiatry, Ohio State University, Columbus.
Acta Psychiatr Scand. 1988 Mar;77(3):241-6. doi: 10.1111/j.1600-0447.1988.tb05116.x.
The authors review the literature discribing non-dyskinetic antipsychotic withdrawal phenomena. Withdrawal of these agents can cause nausea, emesis, anorexia, diarrhea, rhinorrhea, diaphoresis, myalgia, paresthesia, anxiety, agitation, restlessness, and insomnia. Psychotic relapse is often presaged by increased anxiety, agitation, restlessness and insomnia, but the temporal relationship of these prodromal symptoms to reduction in the dosage or discontinuation of neuroleptics distinguishes them from the effects of abrupt withdrawal.
作者回顾了描述非运动障碍性抗精神病药物撤药现象的文献。停用这些药物可导致恶心、呕吐、厌食、腹泻、流涕、发汗、肌痛、感觉异常、焦虑、激动、烦躁不安和失眠。精神病性复发常以焦虑、激动、烦躁不安和失眠加重为先兆，但这些前驱症状与神经阻滞剂剂量减少或停药之间的时间关系将它们与突然撤药的效应区分开来。
