内科-外科环境中的抗精神病药物撤药现象。

Antipsychotic withdrawal phenomena in the medical-surgical setting.

作者信息

Dilsaver S C, Coffman J A

机构信息

Department of Psychiatry, Ohio State University, Columbus 43210-1228.

出版信息

Gen Hosp Psychiatry. 1988 Nov;10(6):438-46. doi: 10.1016/0163-8343(88)90068-0.

DOI:10.1016/0163-8343(88)90068-0

PMID:2904918

Abstract

The literature describing nondyskinetic antipsychotic withdrawal symptoms is reviewed. The withdrawal of antipsychotic agents can result in nausea, emesis, anorexia, diarrhea, rhinorrhea, diaphoresis, myalgias, paresthesias, anxiety, agitation, restlessness, and insomnia. Psychotic relapse is often presaged by increased anxiety, agitation, restlessness, and insomnia. However, the temporal relationship of these prodromal symptoms to reduction in the dosage or discontinuation of neuroleptics distinguishes them from the effects of abrupt withdrawal.

摘要

对描述非运动障碍性抗精神病药物戒断症状的文献进行了综述。抗精神病药物的停用可导致恶心、呕吐、厌食、腹泻、流涕、发汗、肌痛、感觉异常、焦虑、激越、坐立不安和失眠。精神病性复发往往以焦虑增加、激越、坐立不安和失眠为先兆。然而，这些前驱症状与神经阻滞剂剂量减少或停药之间的时间关系将它们与突然停药的效应区分开来。