Alila A, Heavner J E, Rosenberg P H
Department of Anesthesiology, Helsinki University School of Medicine, Finland.
Am J Vet Res. 1988 May;49(5):671-3.
A single extraction technique for measuring pentobarbital and other barbiturates in serum involved high-pressure liquid chromatography and UV detection yielding a sensitivity for pentobarbital of about 1 microgram/ml. We concluded that the assay provides a practical method for use in pharmacokinetic studies and in serum concentration monitoring in experimental animals.
一种用于测定血清中戊巴比妥及其他巴比妥类药物的单一提取技术，涉及高压液相色谱法和紫外线检测，对戊巴比妥的检测灵敏度约为1微克/毫升。我们得出结论，该检测方法为实验动物的药代动力学研究和血清浓度监测提供了一种实用方法。
