Palmarino R, Mantuano E, Lucarelli P
Centro di Genetica Evoluzionistica del CNR, Università La Sapienza, Roma, Italia.
Hum Hered. 1988;38(3):186-8. doi: 10.1159/000153784.
Four Italian populations were examined for a HindIII RFLP associated with the human insulin-like growth factor I gene. No differences were observed among the four samples. The allele frequencies in Italy were: IGF-I HF = 0.834; IGF-I HS = 0.166. The polymorphism appears to be due to a 400-bp sequence insertion-deletion mechanism.
对四个意大利人群进行了检测，以寻找与人类胰岛素样生长因子I基因相关的HindIII限制性片段长度多态性。在这四个样本中未观察到差异。意大利人群中的等位基因频率为：IGF-I HF = 0.834；IGF-I HS = 0.166。这种多态性似乎是由一种400碱基对序列的插入-缺失机制引起的。
