意大利胰岛素样生长因子I的基因变异
Genetic variations of insulin-like growth factor I in Italy.
作者信息
Palmarino R, Mantuano E, Lucarelli P
机构信息
Centro di Genetica Evoluzionistica del CNR, Università La Sapienza, Roma, Italia.
出版信息
Hum Hered. 1988;38(3):186-8. doi: 10.1159/000153784.
PMID:2899544
Abstract
Four Italian populations were examined for a HindIII RFLP associated with the human insulin-like growth factor I gene. No differences were observed among the four samples. The allele frequencies in Italy were: IGF-I HF = 0.834; IGF-I HS = 0.166. The polymorphism appears to be due to a 400-bp sequence insertion-deletion mechanism.
摘要
对四个意大利人群进行了检测，以寻找与人类胰岛素样生长因子I基因相关的HindIII限制性片段长度多态性。在这四个样本中未观察到差异。意大利人群中的等位基因频率为：IGF-I HF = 0.834；IGF-I HS = 0.166。这种多态性似乎是由一种400碱基对序列的插入-缺失机制引起的。
相似文献
1
Genetic variations of insulin-like growth factor I in Italy.意大利胰岛素样生长因子I的基因变异
Hum Hered. 1988;38(3):186-8. doi: 10.1159/000153784.
2
Eco RV RFLP at the insulin-like growth factor I (IGF I) locus on chromosome 12.12号染色体上胰岛素样生长因子I（IGF I）基因座的Eco RV限制性片段长度多态性
Nucleic Acids Res. 1988 Sep 26;16(18):9059. doi: 10.1093/nar/16.18.9059.
3
Insulin-like growth factor-I gene analysis in subjects with constitutionally variant stature.体质性身材变异受试者的胰岛素样生长因子-I基因分析
Pediatr Res. 1990 May;27(5):488-91. doi: 10.1203/00006450-199005000-00014.
4
Relationship of insulin-like growth factors system gene polymorphisms with the susceptibility and pathological development of hepatocellular carcinoma.胰岛素样生长因子系统基因多态性与肝细胞癌易感性及病理发展的关系。
Ann Surg Oncol. 2010 Jul;17(7):1808-15. doi: 10.1245/s10434-009-0904-8. Epub 2010 Jan 30.
5
Ava II RFLP at the insulin-like growth factor II (IGF II) locus on chromosome 11.位于11号染色体上胰岛素样生长因子II（IGF II）基因座的Ava II限制性片段长度多态性。
Nucleic Acids Res. 1989 Jan 11;17(1):466. doi: 10.1093/nar/17.1.466.
6
Eco RI RFLP in the human IGF II gene.人类胰岛素样生长因子II基因中的Eco RI限制性片段长度多态性
Nucleic Acids Res. 1988 Mar 25;16(6):2737. doi: 10.1093/nar/16.6.2737.
7
8
Low prevalence of insulin-like growth factor-I gene mutations in human growth disorders.人类生长障碍中胰岛素样生长因子-I基因突变的低发生率。
J Clin Endocrinol Metab. 1990 Mar;70(3):687-92. doi: 10.1210/jcem-70-3-687.
9
Restriction fragment length polymorphism of the D1S1 locus in Italy.意大利D1S1基因座的限制性片段长度多态性
Hum Hered. 1988;38(5):323-5. doi: 10.1159/000153806.
10
BamHI RFLP at the insulin-like growth factor II (IGF2) locus on chromosome 11.位于11号染色体上胰岛素样生长因子II（IGF2）基因座的BamHI限制性片段长度多态性
Nucleic Acids Res. 1987 Sep 25;15(18):7655. doi: 10.1093/nar/15.18.7655.
Zotero 插件