Osser S, Wramsby H, Liedholm P
Department of Obstetrics and Gynecology, University Hospital, Malmö, Sweden.
Int J Fertil. 1988 May-Jun;33(3):207-11.
The zona-free hamster egg penetration test was performed on 74 random consecutive semen samples from men of infertile couples and on 7 men of proven fertility (semen donors). Of these 74 men, 31 had never before delivered a semen sample (Group I), while the remaining 43 had delivered samples before (Group II). The penetration rates were correlated with the parameters of the semen analysis. In Group I, the mean penetration rate was 59%, in Group II, 42%, and among the fertile donors, 52%. No strong correlation was found between hamster egg penetration rates and the various semen parameters. Only the proportion of motile spermatozoa in Group II correlated significantly with the egg penetration test (P less than .05). Differences in methodology make comparison with the results from different laboratories difficult. It is likely that the egg penetration test measures some separate quality of the spermatozoa that may not be clear from the routine semen analysis. The role of the hamster egg penetration test in the investigation of the causes of infertility should be evaluated further.
对74例来自不育夫妇男方的连续随机精液样本以及7名已证实有生育能力的男性（精液捐献者）进行了无透明带仓鼠卵穿透试验。在这74名男性中，31人此前从未提供过精液样本（第一组），而其余43人此前曾提供过样本（第二组）。穿透率与精液分析参数相关。在第一组中，平均穿透率为59%，在第二组中为42%，在有生育能力的捐献者中为52%。未发现仓鼠卵穿透率与各种精液参数之间有强相关性。仅第二组中活动精子的比例与卵穿透试验显著相关（P小于0.05）。方法学上的差异使得与不同实验室的结果进行比较变得困难。卵穿透试验可能检测到了精子某些常规精液分析中不明确的单独质量。仓鼠卵穿透试验在不孕症病因调查中的作用应进一步评估。
