Diagnosis of human heritable defects by recombinant DNA methods.
作者信息
Caskey C T, Gibbs R A, Witkowski J A, Hejtmancik J F
机构信息
Howard Hughes Medical Institute, Baylor College of Medicine, Houston, Texas 77030.
出版信息
Philos Trans R Soc Lond B Biol Sci. 1988 Jun 15;319(1194):353-60. doi: 10.1098/rstb.1988.0056.
PMID:2900528
Abstract
Recombinant DNA methods provide highly sensitive means for the detection of DNA alterations that lead to human disease mutations. In this paper I shall illustrate the approaches currently available and discuss new technologies that show promise of replacing the present methods. Medical diagnosis by means of recombinant DNA methods has an expanding role in clinical medicine.
摘要
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