Konstantinov G S, Blokhin A V
Arkh Patol. 1988;50(4):44-50.
Amebiasis--a protozoan human disease caused by Entamoeba histolytica--occurs in the USSR sporadically in particular geographic regions and in particular populations. The paper reports morphologic findings made in patients with amebiasis involving the intestine or other organs. In typical cases, amebiasis affects the large intestine, particularly the cecum and ascending colon, and has the development of distinctive ulcers as its characteristic feature. As the disease progresses, these appear in all parts of the large intestine; less commonly, the terminal portion of the small intestine is also involved. The most frequent complications of amebic colitis are perforation and phlegmon, which result in peritonitis. Not infrequently, amebic abscesses arise in the liver or other organs through hematogenous dissemination of amebas. Histologic diagnosis of amebiasis may be difficult. Recommendations on how to detect amebas and the tissue changes peculiar to amebiasis are given.
阿米巴病——一种由溶组织内阿米巴引起的原生动物性人类疾病——在苏联特定地理区域和特定人群中呈散发性出现。本文报告了肠道或其他器官受累的阿米巴病患者的形态学检查结果。在典型病例中,阿米巴病累及大肠,尤其是盲肠和升结肠,其特征性表现为形成独特的溃疡。随着病情进展,这些溃疡出现在大肠的各个部位;较少见的是,小肠末端也会受累。阿米巴性结肠炎最常见的并发症是穿孔和蜂窝织炎,可导致腹膜炎。阿米巴还可通过血行播散至肝脏或其他器官,导致阿米巴脓肿,这种情况也并不罕见。阿米巴病的组织学诊断可能存在困难。文中给出了关于如何检测阿米巴以及阿米巴病特有的组织变化的建议。