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双侧肾动脉狭窄所致高血压中的反复性肺水肿:血管成形术或外科血管重建术治疗

Recurrent pulmonary oedema in hypertension due to bilateral renal artery stenosis: treatment by angioplasty or surgical revascularisation.

作者信息

Pickering T G, Herman L, Devereux R B, Sotelo J E, James G D, Sos T A, Silane M F, Laragh J H

机构信息

Cardiovascular Center, New York Hospital-Cornell University Medical College, New York, NY 10021.

出版信息

Lancet. 1988 Sep 3;2(8610):551-2. doi: 10.1016/s0140-6736(88)92668-2.

Abstract

11 patients with atheromatous renovascular hypertension had a history of multiple episodes of pulmonary oedema. 7 had stenosis of both renal arteries, 2 had stenosis of the artery to a solitary kidney, and 2 had unilateral stenosis with an intact contralateral kidney. Successful revascularisation (by angioplasty in 8, and surgery in 3) improved blood pressure and renal function, and virtually eliminated pulmonary oedema. In a second series of 55 consecutive patients with azotaemia and renovascular hypertension, pulmonary oedema occurred in 13 (23%). Blood pressure and renal function were not significant predictors of pulmonary oedema, but coronary heart disease and bilateral (vs unilateral) renal artery stenosis were. Bilateral renal artery stenosis may be a specific and treatable predisposing factor to pulmonary oedema in azotaemic hypertensive patients.

摘要

11例动脉粥样硬化性肾血管性高血压患者有多次肺水肿发作史。7例双侧肾动脉狭窄,2例单肾动脉狭窄,2例单侧狭窄而对侧肾正常。成功的血管重建术(8例行血管成形术,3例行手术)改善了血压和肾功能,几乎消除了肺水肿。在另一组连续的55例氮质血症和肾血管性高血压患者中,13例(23%)发生了肺水肿。血压和肾功能不是肺水肿的显著预测因素,但冠心病和双侧(与单侧相比)肾动脉狭窄是。双侧肾动脉狭窄可能是氮质血症性高血压患者发生肺水肿的一个特定且可治疗的易感因素。

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