Coulton Simon, Bland Martin, Crosby Helen, Dale Veronica, Drummond Colin, Godfrey Christine, Kaner Eileen, Sweetman Jennifer, McGovern Ruth, Newbury-Birch Dorothy, Parrott Steve, Tober Gillian, Watson Judith, Wu Qi
Centre for Health Service Studies, University of Kent, Canterbury CT2 7NZ, UK.
Department of Health Sciences, University of York, York YO10 5DD, UK.
Alcohol Alcohol. 2017 Nov 1;52(6):655-664. doi: 10.1093/alcalc/agx065.
To compare the clinical effectiveness and cost-effectiveness of a stepped-care intervention versus a minimal intervention for the treatment of older hazardous alcohol users in primary care.
Multi-centre, pragmatic RCT, set in Primary Care in UK. Patients aged ≥ 55 years scoring ≥ 8 on the Alcohol Use Disorders Identification Test were allocated either to 5-min of brief advice or to 'Stepped Care': an initial 20-min of behavioural change counselling, with Step 2 being three sessions of Motivational Enhancement Therapy and Step 3 referral to local alcohol services (progression between each Step being determined by outcomes 1 month after each Step). Outcome measures included average drinks per day, AUDIT-C, alcohol-related problems using the Drinking Problems Index, health-related quality of life using the Short Form 12, costs measured from a NHS/Personal Social Care perspective and estimated health gains in quality adjusted life-years measured assessed EQ-5D.
Both groups reduced alcohol consumption at 12 months but the difference between groups was small and not significant. No significant differences were observed between the groups on secondary outcomes. In economic terms stepped care was less costly and more effective than the minimal intervention.
Stepped care does not confer an advantage over a minimal intervention in terms of reduction in alcohol use for older hazardous alcohol users in primary care. However, stepped care has a greater probability of being more cost-effective.
Current controlled trials ISRCTN52557360.
A stepped care approach was compared with brief intervention for older at-risk drinkers attending primary care. While consumption reduced in both groups over 12 months there was no significant difference between the groups. An economic analysis indicated the stepped care which had a greater probability of being more cost-effective than brief intervention.
比较逐步护理干预与最低限度干预对初级保健中老年有害饮酒者的临床疗效和成本效益。
在英国初级保健机构中进行的多中心实用随机对照试验。年龄≥55岁且酒精使用障碍识别测试得分≥8分的患者被分配接受5分钟的简短建议或“逐步护理”:初始20分钟的行为改变咨询,第二步是三次动机增强治疗,第三步是转介至当地酒精服务机构(每一步之间的进展由每一步后1个月的结果决定)。结果指标包括每日平均饮酒量、酒精使用障碍识别测试-消费版(AUDIT-C)、使用饮酒问题指数评估的与酒精相关的问题、使用简短健康调查问卷12评估的与健康相关的生活质量、从国民保健服务/个人社会护理角度衡量的成本以及使用欧洲五维度健康量表(EQ-5D)评估的质量调整生命年中估计的健康收益。
两组在12个月时均减少了酒精摄入量,但组间差异较小且无统计学意义。在次要结果方面,两组之间未观察到显著差异。在经济方面,逐步护理比最低限度干预成本更低且更有效。
对于初级保健中的老年有害饮酒者,在减少酒精使用方面,逐步护理并不比最低限度干预更具优势。然而,逐步护理更有可能具有更高的成本效益。
当前对照试验ISRCTN52557360。
将逐步护理方法与针对初级保健中高危老年饮酒者的简短干预进行了比较。虽然两组在12个月内饮酒量均有所减少,但组间无显著差异。一项经济分析表明,逐步护理比简短干预更有可能具有更高的成本效益。