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心脏移植后保留的起搏器和植入式心脏复律除颤器组件很常见,可能导致不良事件。

Retained pacemaker and implantable cardioverter-defibrillator components after heart transplantation are common and may lead to adverse events.

机构信息

Transplant Unit, Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge, UK.

出版信息

Europace. 2018 Aug 1;20(8):1312-1317. doi: 10.1093/europace/eux213.

Abstract

AIMS

Many patients have a cardiac implantable electronic device (CIED) extracted at the time of heart transplantation. CIED components may be retained after heart transplantation, but their frequency, nature, and clinical significance is uncertain.

METHODS AND RESULTS

Consecutive patients that underwent heart transplantation over 10 years from 1 January 2007 until 1 January 2017 were identified from the unit database. Pre- and post-operative chest radiographs were reviewed by two independent observers for the presence of CIED components. Adverse events relating to any retained CIED component were recorded. Two hundred and six patients had a CIED removed at the time of transplantation. Retained CIED components were present in 86 (42%) patients. The most common retained CIED components were suture sleeves and superior vena cava (SVC) coils of dual coil implantable cardioverter-defibrillator (ICD) leads. An SVC coil was retained in 25% of patients that had a dual coil ICD lead. Seven adverse events were associated with CIED removal or retained CIED components, including one fatal event. However, retained CIED components were not associated with reduced long-term survival after heart transplantation.

CONCLUSION

Retained CIED components were seen in 42% of patients that had a CIED prior to transplantation, may be associated with serious adverse events but are not associated with reduced long-term survival. Cardiac surgeons should be aware of all CIED system components and be familiar with techniques for their complete removal at the time of transplantation.

摘要

目的

许多患者在进行心脏移植时会取出心脏植入式电子设备(CIED)。CIED 组件在心脏移植后可能会保留,但它们的频率、性质和临床意义尚不确定。

方法和结果

从 2007 年 1 月 1 日至 2017 年 1 月 1 日的 10 年间,从单位数据库中确定了连续接受心脏移植的患者。由两名独立观察者对术前和术后的胸部 X 线片进行复查,以确定是否存在 CIED 组件。记录与任何保留的 CIED 组件相关的不良事件。有 206 例患者在移植时移除了 CIED。86 例(42%)患者仍存在 CIED 组件。最常见的保留的 CIED 组件是双线圈植入式心律转复除颤器(ICD)引线的缝合套管和上腔静脉(SVC)线圈。在接受双线圈 ICD 引线的患者中,有 25%的患者保留了 SVC 线圈。与 CIED 移除或保留的 CIED 组件相关的有 7 例不良事件,包括 1 例致命事件。然而,保留的 CIED 组件与心脏移植后长期生存降低无关。

结论

在进行心脏移植前有 CIED 的患者中,有 42%的患者存在保留的 CIED 组件,可能与严重不良事件有关,但与长期生存降低无关。心脏外科医生应该了解所有 CIED 系统组件,并熟悉在移植时完全移除它们的技术。

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