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塑料支架与金属支架用于远端胆管梗阻患者胆管减压的对比研究。

Comparative Study between Plastic and Metallic Stents for Biliary Decompression in Patients with Distal Biliary Obstruction.

作者信息

Cabral João Guilherme G, Taglieri Eloy, Pelosof Adriane, Rosendo Daniel, Ardengh José Celso

机构信息

Endoscopy Service of Hospital A. C. Camargo, São Paulo, SP, Brazil.

Endoscopy Service of Hospital 9 de Julho, São Paulo, SP, Brazil.

出版信息

Gastroenterol Res Pract. 2017;2017:7621821. doi: 10.1155/2017/7621821. Epub 2017 Sep 6.

Abstract

This paper presents a retrospective comparison of plastic versus metallic stents in the drainage of malignant distal biliary obstructions. We compared single plastic stents (SPS), multiple plastic stents (MPS), and metallic stents (SEMS) regarding clinical decrease of TB < 2.0 mg/dL, long-term patency, and adverse event. 58 patients (38 women) with MDBO were included. Diagnoses were 44 pancreatic adenocarcinoma (74.6%), 9 metastasis (15.5%), 3 pancreatic neuroendocrine tumors (5.1%), and 2 adenocarcinoma in the major papilla (3.4%). The number of patients included in the SPS, MPS, and SEMS was 17, 6, and 35, respectively. Comparing the survival curves with respect to obstruction, we observed a lower mean permeability of the SPS compared to that of the MPS with < 0.003 and of the SEMS group ( < 0.01). There was no statistical difference between the use of MPS, despite the small number of patients compared to the use of SEMS ( < 0.13) to reach the satisfactory levels of bilirubin.

摘要

本文对塑料支架与金属支架在恶性远端胆管梗阻引流中的应用进行了回顾性比较。我们比较了单根塑料支架(SPS)、多根塑料支架(MPS)和金属支架(SEMS)在总胆红素(TB)降至<2.0mg/dL的临床效果、长期通畅率及不良事件方面的差异。纳入了58例恶性远端胆管梗阻患者(38例女性)。诊断包括44例胰腺腺癌(74.6%)、9例转移瘤(15.5%)、3例胰腺神经内分泌肿瘤(5.1%)和2例主乳头腺癌(3.4%)。SPS、MPS和SEMS组纳入的患者数分别为17例、6例和35例。比较梗阻相关的生存曲线,我们观察到SPS的平均通畅率低于MPS(P<0.003)和SEMS组(P<0.01)。尽管与SEMS组相比,MPS组患者数量较少,但在使胆红素达到满意水平方面,二者无统计学差异(P<0.13)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3dc/5606050/3c224c0d7417/GRP2017-7621821.001.jpg

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