Tsao Wei-Shan, He Ming-Shan, Tsai Rong-Kung
Department of Ophthalmology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Institute of Eye Research, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.
Taiwan J Ophthalmol. 2015 Oct-Dec;5(4):189-191. doi: 10.1016/j.tjo.2014.10.001. Epub 2014 Nov 20.
Varicella zoster virus-associated neuroretinitis is rare. We report a patient who presented with blurred vision of the left eye and extraocular movement pain. A fundoscopic examination revealed disc edema, hyperemia, and macular edema. The impression was neuroretinitis. Intravenous methylprednisolone pulse therapy was administered. However, visual recovery was incomplete with optical coherence tomography (OCT) imaging showing photoreceptor layer disruption. The laboratory data were rechecked and demonstrated a high varicella zoster virus immunoglobulin G titer. Varicella zoster virus-associated neuroretinitis was suspected and oral acyclovir was prescribed. His visual acuity improved to 0.9 after 2 weeks of treatment, and OCT showed photoreceptor layer restoration. Spectrum-domain OCT provides useful information when evaluating the disease course of neuroretinitis.
水痘带状疱疹病毒相关性神经视网膜炎较为罕见。我们报告一名患者，其出现左眼视力模糊及眼球运动疼痛。眼底检查发现视盘水肿、充血及黄斑水肿。诊断为神经视网膜炎。给予静脉注射甲泼尼龙冲击治疗。然而，光学相干断层扫描（OCT）成像显示光感受器层破坏，视力恢复不完全。复查实验室数据显示水痘带状疱疹病毒免疫球蛋白G滴度较高。怀疑为水痘带状疱疹病毒相关性神经视网膜炎，并开具口服阿昔洛韦。治疗2周后其视力提高至0.9，OCT显示光感受器层恢复。光谱域OCT在评估神经视网膜炎病程时可提供有用信息。
