Tosoni Simone, Tarzia Vincenzo, Colli Andrea, Gerosa Gino, Bagno Andrea
Department of Industrial Engineering, University of Padua, via Marzolo 9, 35131, Padua, Italy.
Cardiac Surgery Unit, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy.
J Artif Organs. 2017 Dec;20(4):394-398. doi: 10.1007/s10047-017-1002-5. Epub 2017 Oct 10.
The formation of thrombotic deposits affects the functionality of mechanical prosthetic heart valves; as a consequence, mechanical valves thrombosis needs early diagnosis to prevent thromboembolic events. This paper compares the acoustic signals produced by two commercial bileaflet mechanical heart valves in the closing phase to detect the presence of thrombi. The closing sounds were recorded in vitro by means of a phonocardiographic device under different hydrodynamic conditions. Thrombotic deposits of different weight and shape were applied onto the valve leaflet and the annular housing, until the movement of one leaflet was completely blocked. From the acoustic signals, the corresponding spectra were calculated and four diagnostic frequency bands were identified: their comparison allowed detecting malfunctioning valves because of the presence of thrombotic formations.
血栓沉积物的形成会影响机械人工心脏瓣膜的功能；因此，机械瓣膜血栓形成需要早期诊断以预防血栓栓塞事件。本文比较了两种商用双叶机械心脏瓣膜在关闭阶段产生的声学信号，以检测血栓的存在。通过心音图设备在不同的流体动力学条件下在体外记录关闭声音。将不同重量和形状的血栓沉积物施加到瓣膜小叶和环形外壳上，直到一个小叶的运动完全受阻。从声学信号中计算出相应的频谱，并确定了四个诊断频带：通过比较这些频带可以检测出由于血栓形成而出现故障的瓣膜。
