Ebert Andreas, Brüne Martin
LWL University Hospital Bochum, Department of Psychiatry, Psychotherapy and Preventive Medicine, Division of Cognitive Neuropsychiatry and Psychiatric Preventive Medicine, Ruhr-University Bochum, Bochum, Germany.
Curr Top Behav Neurosci. 2018;35:375-388. doi: 10.1007/7854_2017_21.
Oxytocin has been linked to many domains within the realm of "social cognition." For example, research has shown that oxytocin affects trusting behavior, cooperation, as well as the perception and processing of facial expressions. Furthermore, oxytocin increases empathy and seems to exert differential effects on in-group versus out-group preferences. However, there are some conflicting results that point towards a modulatory effect of oxytocin, depending on a variety of contextual and within-subject factors. Research about the underlying mechanisms (e.g., neural circuits and genetics) indicates that the modulation of amygdala activity by oxytocin is elementary for the understanding of social cognitive processes. As regards genetics, several variants of the oxytocin receptor gene (OXTR) have been extensively studied in relation to social cognition. Taken together, oxytocin is an important modulator of social cognitive processes, although substantially more research is needed in order to understand the complexity of oxytocinergic effects on social perception, cognition, and interpersonal behavior.
催产素与“社会认知”领域内的许多方面都有关联。例如,研究表明催产素会影响信任行为、合作以及对面部表情的感知和处理。此外,催产素会增强同理心,并且似乎对群体内偏好和群体外偏好产生不同影响。然而,也有一些相互矛盾的结果表明,催产素的调节作用取决于多种情境因素和个体内部因素。关于潜在机制(如神经回路和遗传学)的研究表明,催产素对杏仁核活动的调节对于理解社会认知过程至关重要。在遗传学方面,催产素受体基因(OXTR)的几种变体已经在与社会认知相关的研究中得到了广泛研究。综上所述,催产素是社会认知过程的重要调节因子,不过,为了理解催产素能对社会感知、认知和人际行为产生的复杂影响,仍需要进行大量的研究。