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根治性腹腔镜肝切除术治疗恶性肝肿瘤的长期疗效的批判性评估

CRITICAL EVALUATION OF LONG-TERM RESULTS OF MALIGNANT HEPATIC TUMORS TREATED BY MEANS CURATIVE LAPAROSCOPIC HEPATECTOMY.

作者信息

Pais-Costa Sergio Renato, Araújo Sergio Luiz Melo, Lima Olímpia Alves Teixeira, Martins Sandro José

机构信息

Hospital Santa Lucia.

Hospital Brasília, Brasília, DF, Brazil.

出版信息

Arq Bras Cir Dig. 2017 Jul-Sep;30(3):205-210. doi: 10.1590/0102-6720201700030010.

DOI:10.1590/0102-6720201700030010
PMID:29019563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5630215/
Abstract

BACKGROUND

Laparoscopic hepatectomy has presented great importance for treating malignant hepatic lesions.

AIM

To evaluate its impact in relation to overall survival or disease free of the patients operated due different hepatic malignant tumors.

METHODS

Thirty-four laparoscopic hepatectomies were performed in 31 patients with malignant neoplasm. Patients were distributed as: Group 1 - colorectal metastases (n=14); Group 2 - hepatocellular carcinoma (n=8); and Group 3 - non-colorectal metastases and intrahepatic cholangiocarcinoma (n=9). The conversion rate, morbidity, mortality and tumor recurrence were also evaluated.

RESULTS

Conversion to open surgery was 6%; morbidity 22%; postoperative mortality 3%. There was tumor recurrence in 11 cases. Medians of overall survival and disease free survival were respectively 60 and 46 m; however, there was no difference among studied groups (p>0,05).

CONCLUSION

Long-term outcomes of laparoscopic hepatectomy for treating hepatic malignant tumors are satisfactory. There is no statistical difference in relation of both overall and disease free survival among different groups of hepatic neoplasms.

摘要

背景

腹腔镜肝切除术对治疗肝脏恶性病变具有重要意义。

目的

评估其对因不同肝脏恶性肿瘤接受手术患者的总生存期或无病生存期的影响。

方法

对31例恶性肿瘤患者实施了34例腹腔镜肝切除术。患者分为:第1组 - 结直肠癌转移(n = 14);第2组 - 肝细胞癌(n = 8);第3组 - 非结直肠癌转移和肝内胆管癌(n = 9)。还评估了中转率、发病率、死亡率和肿瘤复发情况。

结果

中转开腹手术率为6%;发病率为22%;术后死亡率为3%。11例出现肿瘤复发。总生存期和无病生存期的中位数分别为60个月和46个月;然而,各研究组之间无差异(p>0.05)。

结论

腹腔镜肝切除术治疗肝脏恶性肿瘤的长期效果令人满意。不同组肝脏肿瘤在总生存期和无病生存期方面无统计学差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e20e/5630215/e208cb36eedc/0102-6720-abcd-30-03-00205-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e20e/5630215/63bcf76202c3/0102-6720-abcd-30-03-00205-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e20e/5630215/e208cb36eedc/0102-6720-abcd-30-03-00205-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e20e/5630215/63bcf76202c3/0102-6720-abcd-30-03-00205-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e20e/5630215/e208cb36eedc/0102-6720-abcd-30-03-00205-gf2.jpg

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