基于人群的结直肠癌筛查 2 年随访中的生活方式。

Lifestyle in population-based colorectal cancer screening over 2-year follow-up.

机构信息

Mass Screening Registry, Finnish Cancer Registry, Helsinki, Finland.

Department of Public Health, University of Helsinki, Helsinki, Finland.

出版信息

Eur J Public Health. 2018 Apr 1;28(2):333-338. doi: 10.1093/eurpub/ckx139.

DOI:10.1093/eurpub/ckx139

PMID:29020299

Abstract

BACKGROUND

Colorectal cancer (CRC) screening may cause changes in health-related lifestyle. In 2010, Finnish Mass Screening Registry began a study on psychosocial effects of CRC screening. This article examines whether there are differential developments in self-reported lifestyle at ages 59-61 years among CRC screening invitees and non-contacted controls.

METHODS

A population-based random sample of 10 648 Finnish adults born in 1951 and living in the municipalities voluntary involved in the CRC screening programme were sent a lifestyle questionnaire in 2010. In 2011, the cohort was randomised (1 : 1) for their first ever CRC screening at age 60 or for controls. The questionnaires were repeated in 2012 for all. From both survey rounds, 2508 pairs of completed questionnaires were available for analysis from the screening group and 2387 from the control group. The outcome was 2-year change in total lifestyle index of CRC risk factors (diet, physical activity, body mass index, alcohol consumption and smoking).

RESULTS

Total lifestyle index decreased throughout the follow-up in both the screening group [odds ratio (OR) = 0.80, 95% confidence interval (CI) 0.72-0.90] and in the control group (OR = 0.80, CI 0.71-0.90) indicating no difference in lifestyle changes between groups. There was also no significant difference by screening participation: the change in score was similar in those participating screening (OR 0.81, CI 0.72-0.92) and in those invited, but not participating (OR 0.75, CI 0.55-1.03).

CONCLUSION

Present study found no unfavourable changes in total lifestyle in the studied age group due to CRC screening. Results are reassuring from the point of view of CRC screening evaluation.

摘要

背景

结直肠癌（CRC）筛查可能会改变与健康相关的生活方式。2010 年，芬兰大规模筛查登记处开始研究 CRC 筛查的心理社会影响。本文研究了在接受 CRC 筛查邀请和未联系对照者中，59-61 岁时自我报告的生活方式是否存在差异。

方法

一项基于人群的随机抽样研究，共纳入 10648 名 1951 年出生、居住在自愿参与 CRC 筛查计划的芬兰市镇的成年人。2010 年，这些人收到了一份生活方式问卷。2011 年，该队列按 1:1 随机分配到 60 岁时首次进行 CRC 筛查或对照组。所有人均在 2012 年重复进行了问卷调查。在筛查组和对照组中，各有 2508 对和 2387 对完成的问卷可供分析。主要结局为 CRC 风险因素（饮食、体力活动、体重指数、饮酒和吸烟）的总生活方式指数的 2 年变化。

结果

在整个随访期间，筛查组（OR=0.80，95%CI 0.72-0.90）和对照组（OR=0.80，95%CI 0.71-0.90）的总生活方式指数均呈下降趋势，表明两组之间的生活方式变化无差异。筛查参与也无显著差异：参加筛查（OR 0.81，95%CI 0.72-0.92）和受邀但未参加筛查（OR 0.75，95%CI 0.55-1.03）者的评分变化相似。