Roth Bettlach Carrie L, Hasak Jessica M, Krauss Emily M, Yu Jenny L, Skolnick Gary B, Bodway Greta N, Kahn Lorna C, Mackinnon Susan E
1 Washington University School of Medicine in Saint Louis, MO, USA.
2 University of British Columbia, Vancouver, Canada.
Hand (N Y). 2019 Mar;14(2):163-171. doi: 10.1177/1558944717735942. Epub 2017 Oct 11.
Carpal tunnel syndrome has been associated with sleep position preferences. The aim of this study is to assess self-reported nocturnal paresthesias and sleeping position in participants with and without carpal tunnel syndrome diagnosis to further clinical knowledge for preventive and therapeutic interventions.
A cross-sectional survey study of 396 participants was performed in young adults, healthy volunteers, and a patient population. Participants were surveyed on risk factors for carpal tunnel syndrome, nocturnal paresthesias, and sleep preferences. Binary logistic regression analysis was performed comparing participants with rare and frequent nocturnal paresthesias. Subanalyses for participants without carpal tunnel syndrome under and over 21 years of age were performed on all factors significantly associated with subclinical compression neuropathy in the overall population.
Thirty-three percent of the study population experienced nocturnal paresthesias at least weekly. Increased body mass index ( P < .001) and sleeping with the wrist flexed ( P = .030) were associated with a higher frequency of nocturnal paresthesias. Side sleeping was associated with less frequent nocturnal symptoms ( P = .003). In participants without carpal tunnel syndrome, subgroup analysis illustrated a relationship between nocturnal paresthesias and wrist position. In participants with carpal tunnel syndrome, sleeping on the side had a significantly reduced frequency of nocturnal paresthesias.
This study illustrates nocturnal paresthesias in people without history of carpal tunnel syndrome including people younger than previously reported. In healthy patients with upper extremity subclinical compression neuropathy, sleep position modification may be a useful intervention to reduce the frequency of nocturnal symptoms prior to developing carpal tunnel syndrome.
腕管综合征与睡眠姿势偏好有关。本研究的目的是评估有和没有腕管综合征诊断的参与者自我报告的夜间感觉异常和睡眠姿势，以增进预防和治疗干预的临床知识。
对396名参与者进行了一项横断面调查研究，参与者包括年轻人、健康志愿者和患者群体。对参与者进行了关于腕管综合征的危险因素、夜间感觉异常和睡眠偏好的调查。进行二元逻辑回归分析，比较夜间感觉异常罕见和频繁的参与者。对所有与总体人群亚临床压迫性神经病变显著相关的因素，对21岁以下和21岁以上无腕管综合征的参与者进行亚分析。
33%的研究人群至少每周经历一次夜间感觉异常。体重指数增加（P <.001）和手腕屈曲睡眠（P =.030）与夜间感觉异常频率较高有关。侧卧睡眠与夜间症状频率较低有关（P =.003）。在无腕管综合征的参与者中，亚组分析表明夜间感觉异常与手腕位置之间存在关系。在患有腕管综合征的参与者中，侧卧睡眠显著降低了夜间感觉异常的频率。
本研究表明，在无腕管综合征病史的人群中存在夜间感觉异常，包括比以前报道的更年轻的人群。在患有上肢亚临床压迫性神经病变的健康患者中，改变睡眠姿势可能是一种有用的干预措施，可在发展为腕管综合征之前降低夜间症状的频率。
