Sood Anshuman, Hakim David, Bose Abhishek
Department of Medicine and Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.
Department of Urology, Narayan Medical College and Hospital, Jamuhar, Sasaram, Bihar, India.
Indian J Urol. 2017 Oct-Dec;33(4):328-330. doi: 10.4103/iju.IJU_10_16.
HIV-associated nephropathy (HIVAN) is a pathological state of the kidneys due to longstanding, uncontrolled HIV infection. With the rapid progression of HIVAN to end-stage kidney failure, there is a significant potential for renal transplantation to improve the quality of life in these patients. Numerous studies have been recently published documenting renal transplantation as a primary treatment for HIVAN. With the use of highly active antiretroviral therapy, allograft and patient survival rates of HIV-infected persons are nearly identical to those who are HIV negative. Our case study documents the successful role of renal transplantation in treating HIVAN in a 9-year-old male child.
人类免疫缺陷病毒相关性肾病(HIVAN)是由于长期未得到控制的HIV感染而导致的一种肾脏病理状态。随着HIVAN迅速进展至终末期肾衰竭,肾移植对于改善这些患者的生活质量具有巨大潜力。最近发表了大量研究,记录了肾移植作为HIVAN的主要治疗方法。通过使用高效抗逆转录病毒疗法,HIV感染者的同种异体肾移植和患者存活率与HIV阴性者几乎相同。我们的病例研究记录了肾移植在一名9岁男童HIVAN治疗中的成功作用。