Chong Yosep, Lee Young Sub, Kim Tae-Jung, Park Woo-Chan, Kang Chang Suk, Lee Eun Jung
Address: Department of Hospital Pathology, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Cytojournal. 2017 Sep 25;14:23. doi: 10.4103/cytojournal.cytojournal_3_17. eCollection 2017.
Spindle cell ductal carcinoma (DCIS) is a recently recognized subtype of DCIS, which is associated with a very rare and unique morphology. Although the histologic features have been relatively well described in a few reports, the cytologic features have not. Even though the distinction of this lesion from usual DCIS is not crucial clinically, it should be noted that this lesion might simulate the features of metaplastic carcinoma on fine needle aspiration cytology. Here, we report a case of spindle cell DCIS in a 45-year-old female, with the detailed cytologic features, both on conventional and liquid-based preparations, along with some useful immunohistochemical staining markers for the differential diagnosis.
梭形细胞导管原位癌(DCIS)是一种最近才被认识到的DCIS亚型,其具有非常罕见且独特的形态。尽管在一些报告中对其组织学特征已有相对较好的描述,但细胞学特征尚未见报道。即使该病变与普通DCIS在临床上的区分并不关键,但应注意的是,在细针穿刺细胞学检查中,此病变可能会模拟化生性癌的特征。在此,我们报告一例45岁女性的梭形细胞DCIS病例,详细描述了其在传统涂片和液基制片上的细胞学特征,以及一些有助于鉴别诊断的免疫组化染色标记物。